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Influence of cardiac hemodynamic parameters on coronary artery opacification with 64-slice computed tomography


Husmann, Lars; Alkadhi, Hatem; Boehm, Thomas; Leschka, Sebastian; Schepis, Tiziano; Koepfli, Pascal; Desbiolles, Lotus; Marincek, Borut; Kaufmann, Philipp A; Wildermuth, Simon (2006). Influence of cardiac hemodynamic parameters on coronary artery opacification with 64-slice computed tomography. European Radiology, 16(5):1111-1116.

Abstract

The purpose of this study was to evaluate the influence of ejection fraction (EF), stroke volume (SV), heart rate, and cardiac output (CO) on coronary artery opacification with 64-slice computed tomography (CT). Sixty patients underwent, retrospectively, electrocardiography-gated 64-slice CT coronary angiography. Left ventricular EF, SV, and CO were calculated with semi-automated software. Attenuation values were measured and contrast-to-noise ratios (CNRs) were calculated in the proximal right coronary artery (RCA) and left main artery (LMA). Mean EF during scanning was 61.5±12.4%, SV was 63.2±15.6ml, heart rate was 62.5±11.8beats per minute (bpm), and CO was 3.88±1.06l/min. There was no significant correlation between the EF and heart rate and the attenuation and CNR in either coronary artery. A significant negative correlation was found in both arteries between SV and attenuation (RCA r=−0.26, P<0.05; LMA r=−0.34, P<0.01) and between SV and CNR (RCA r=−0.26, P<0.05; LMA r=−0.26, P<0.05). Similarly, a significant negative correlation was found between the CO and attenuation (RCA r=−0.42, P<0.05; LMA r=−0.56, P<0.001) and between the CO and CNR (RCA r=−0.39, P<0.05; LMA r=−0.44, P<0.001). The actual hemodynamic status of the patient influences the coronary artery opacification with 64-slice CT, in that vessel opacification decreases as SV and CO increase

Abstract

The purpose of this study was to evaluate the influence of ejection fraction (EF), stroke volume (SV), heart rate, and cardiac output (CO) on coronary artery opacification with 64-slice computed tomography (CT). Sixty patients underwent, retrospectively, electrocardiography-gated 64-slice CT coronary angiography. Left ventricular EF, SV, and CO were calculated with semi-automated software. Attenuation values were measured and contrast-to-noise ratios (CNRs) were calculated in the proximal right coronary artery (RCA) and left main artery (LMA). Mean EF during scanning was 61.5±12.4%, SV was 63.2±15.6ml, heart rate was 62.5±11.8beats per minute (bpm), and CO was 3.88±1.06l/min. There was no significant correlation between the EF and heart rate and the attenuation and CNR in either coronary artery. A significant negative correlation was found in both arteries between SV and attenuation (RCA r=−0.26, P<0.05; LMA r=−0.34, P<0.01) and between SV and CNR (RCA r=−0.26, P<0.05; LMA r=−0.26, P<0.05). Similarly, a significant negative correlation was found between the CO and attenuation (RCA r=−0.42, P<0.05; LMA r=−0.56, P<0.001) and between the CO and CNR (RCA r=−0.39, P<0.05; LMA r=−0.44, P<0.001). The actual hemodynamic status of the patient influences the coronary artery opacification with 64-slice CT, in that vessel opacification decreases as SV and CO increase

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Item Type:Journal Article, refereed, original work
Communities & Collections:National licences > 142-005
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:10 April 2006
Deposited On:13 Dec 2018 17:09
Last Modified:26 Apr 2019 22:32
Publisher:Springer
ISSN:0938-7994
OA Status:Green
Publisher DOI:https://doi.org/10.1007/s00330-005-0110-4
Related URLs:https://www.swissbib.ch/Search/Results?lookfor=nationallicencespringer101007s0033000501104 (Library Catalogue)

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