Header

UZH-Logo

Maintenance Infos

Long-term follow-up after combined fissurectomy and Botox injection for chronic anal fissures


Scholz, T; Hetzer, F H; Dindo, D; Demartines, N; Clavien, P A; Hahnloser, D (2007). Long-term follow-up after combined fissurectomy and Botox injection for chronic anal fissures. International journal of colorectal disease, 22(9):1077-1081.

Abstract

Background and aims: Chronic anal fissures are difficult to treat. The aim of this retrospective study was to determine the outcome of combined fissurectomy and injection of botulinum toxin Type A (BT). Materials and methods: Between January 2001 and August 2004, 40 patients (21 women), median age 37years (range 18 to 57), underwent fissurectomy and BT injection. Fissurectomy was performed followed by injection of 10U of BT into the internal anal sphincter on both sides of the fissure. All patients were clinically checked 6weeks after the operation. At 1year, patients were sent a detailed questionnaire regarding symptoms, recurrence and further treatment for evaluation of long-term results. Results/findings: At 6weeks, 38 patients (95%) were free of symptoms. No adverse effects were detected. The response rate of questionnaires was 93%; the median follow-up was 1year (range 0.9 to 1.6). In the long-term, a recurrence was found in four patients. These patients were treated successfully with repeated fissurectomy and BT injections and salvage procedures, respectively. Overall, the success rate of combined fissurectomy and BT injection was 79%. Interpretation/conclusion: Combined fissurectomy and Botox injection for chronic anal fissure is an excellent and safe procedure with low morbidity and a high healing rate

Abstract

Background and aims: Chronic anal fissures are difficult to treat. The aim of this retrospective study was to determine the outcome of combined fissurectomy and injection of botulinum toxin Type A (BT). Materials and methods: Between January 2001 and August 2004, 40 patients (21 women), median age 37years (range 18 to 57), underwent fissurectomy and BT injection. Fissurectomy was performed followed by injection of 10U of BT into the internal anal sphincter on both sides of the fissure. All patients were clinically checked 6weeks after the operation. At 1year, patients were sent a detailed questionnaire regarding symptoms, recurrence and further treatment for evaluation of long-term results. Results/findings: At 6weeks, 38 patients (95%) were free of symptoms. No adverse effects were detected. The response rate of questionnaires was 93%; the median follow-up was 1year (range 0.9 to 1.6). In the long-term, a recurrence was found in four patients. These patients were treated successfully with repeated fissurectomy and BT injections and salvage procedures, respectively. Overall, the success rate of combined fissurectomy and BT injection was 79%. Interpretation/conclusion: Combined fissurectomy and Botox injection for chronic anal fissure is an excellent and safe procedure with low morbidity and a high healing rate

Statistics

Citations

Dimensions.ai Metrics
34 citations in Web of Science®
37 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

22 downloads since deposited on 21 Dec 2018
22 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:National licences > 142-005
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1 September 2007
Deposited On:21 Dec 2018 17:36
Last Modified:24 Sep 2019 23:47
Publisher:Springer
ISSN:0179-1958
OA Status:Green
Publisher DOI:https://doi.org/10.1007/s00384-006-0261-z
Related URLs:https://www.swissbib.ch/Search/Results?lookfor=nationallicencespringer101007s003840060261z (Library Catalogue)

Download

Download PDF  'Long-term follow-up after combined fissurectomy and Botox injection for chronic anal fissures'.
Preview
Content: Published Version
Language: English
Filetype: PDF (Nationallizenz 142-005)
Size: 120kB
View at publisher