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Are behavioral problems in childhood and adolescence associated with bipolar disorder in early adulthood?


Endrass, Jérôme; Vetter, Stefan; Gamma, Alex; Gallo, William T; Rossegger, Astrid; Urbaniok, Frank; Angst, Jules (2007). Are behavioral problems in childhood and adolescence associated with bipolar disorder in early adulthood? European Archives of Psychiatry and Clinical Neuroscience, 257(4):217-221.

Abstract

Several recent studies have found an association between conduct problems and bipolar disorder in adolescents. However, prospective studies are rare and most do not apply multivariable analysis strategies to control for important variables (e.g. socio-demographics). The aim of this study was to test the association between certain conduct problems and bipolar disorders. The sample consisted of 591 adolescents (male and female) representative for 2,600 persons from the Canton of Zurich in Switzerland. Data were prospectively collected through an interviewing procedure, with the first screening taking place at the age of 19-20. The incidence rate was computed using sampling weights, and risk factors of bipolar II disorder were estimated using a multivariable logistic regression model. The 9-year incidence rate of bipolar II disorder in the canton of Zurich was 8.4% (n=65). Adolescents and children showing behavior such as repeated running away from home and physical fighting were 2.6-3.5 times more likely to experience a bipolar II disorder than those with no indication of conduct problems. Sensitivity analysis showed that the conduct problems were not the result of low socio-economic status

Abstract

Several recent studies have found an association between conduct problems and bipolar disorder in adolescents. However, prospective studies are rare and most do not apply multivariable analysis strategies to control for important variables (e.g. socio-demographics). The aim of this study was to test the association between certain conduct problems and bipolar disorders. The sample consisted of 591 adolescents (male and female) representative for 2,600 persons from the Canton of Zurich in Switzerland. Data were prospectively collected through an interviewing procedure, with the first screening taking place at the age of 19-20. The incidence rate was computed using sampling weights, and risk factors of bipolar II disorder were estimated using a multivariable logistic regression model. The 9-year incidence rate of bipolar II disorder in the canton of Zurich was 8.4% (n=65). Adolescents and children showing behavior such as repeated running away from home and physical fighting were 2.6-3.5 times more likely to experience a bipolar II disorder than those with no indication of conduct problems. Sensitivity analysis showed that the conduct problems were not the result of low socio-economic status

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:National licences > 142-005
Dewey Decimal Classification:150 Psychology
Language:English
Date:1 June 2007
Deposited On:03 Jul 2019 13:05
Last Modified:24 Sep 2019 23:47
Publisher:Springer
ISSN:0940-1334
OA Status:Green
Publisher DOI:https://doi.org/10.1007/s00406-006-0710-2
Related URLs:https://www.swissbib.ch/Search/Results?lookfor=nationallicencespringer101007s0040600607102 (Library Catalogue)
PubMed ID:17287927

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