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Comparison of chemically and pharmaceutically modified titanium and zirconia implant surfaces in dentistry: a study in sheep


Langhoff, J D; Voelter-Ratson, K; Scharnweber, D; Schnabelrauch, M; Schlottig, F; Hefti, T; Kalchofner Guerrero, Karin S; Nuss, Katja M; von Rechenberg, Brigitte (2008). Comparison of chemically and pharmaceutically modified titanium and zirconia implant surfaces in dentistry: a study in sheep. International Journal of Oral and Maxillofacial Surgery, 37(12):1125-1132.

Abstract

Abstract: Advanced surface modifications and materials were tested on the same implant geometry. Six types of dental implants were tested for osseointegration after 2, 4 and 8 weeks in a sheep pelvis model. Four titanium implant types were treated with newly developed surface modifications, of which two were chemically and two were pharmacologically modified. One implant was made of zirconia. A sandblasted and acid-etched titanium surface was used as reference. The chemically modified implants were plasma-anodized or coated with calcium phosphate. The pharmacological coatings contained either biphosphonate or collagen type I with chondroitin sulphate. The implants were evaluated using macroscopic, radiographic and histomorphometric methods.
All implants were well osseointegrated at the time of death. All titanium implants had similar bone implant contact (BIC) at 2 weeks (57-61 %); only zirconia was better (77 %). The main BIC increase was between 2 and 4 weeks. The pharmacologically coated implants (78-79 %) and the calcium phosphate coating (85 %) showed similar results compared with the reference implant (80 %) at 8 weeks. There were no significant differences in BIC. Compared with previous studies, the results of all implants were comparatively good.

Abstract

Abstract: Advanced surface modifications and materials were tested on the same implant geometry. Six types of dental implants were tested for osseointegration after 2, 4 and 8 weeks in a sheep pelvis model. Four titanium implant types were treated with newly developed surface modifications, of which two were chemically and two were pharmacologically modified. One implant was made of zirconia. A sandblasted and acid-etched titanium surface was used as reference. The chemically modified implants were plasma-anodized or coated with calcium phosphate. The pharmacological coatings contained either biphosphonate or collagen type I with chondroitin sulphate. The implants were evaluated using macroscopic, radiographic and histomorphometric methods.
All implants were well osseointegrated at the time of death. All titanium implants had similar bone implant contact (BIC) at 2 weeks (57-61 %); only zirconia was better (77 %). The main BIC increase was between 2 and 4 weeks. The pharmacologically coated implants (78-79 %) and the calcium phosphate coating (85 %) showed similar results compared with the reference implant (80 %) at 8 weeks. There were no significant differences in BIC. Compared with previous studies, the results of all implants were comparatively good.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Equine Department
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Language:English
Date:2008
Deposited On:20 Feb 2009 15:58
Last Modified:23 Sep 2018 05:07
Publisher:Elsevier
ISSN:0901-5027
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.ijom.2008.09.008
PubMed ID:18977118

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