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In Vitro Comparisons of Near-Infrared Spectroscopy Oximeters: Impact of Slow Changes in Scattering of Liquid Phantoms


Ostojic, Daniel; Kleiser, Stefan; Nasseri, Nassim; Isler, Helene; Andresen, Bjørn; Wabnitz, Heidrun; Karen, Tanja; Scholkmann, Felix; Wolf, Martin (2018). In Vitro Comparisons of Near-Infrared Spectroscopy Oximeters: Impact of Slow Changes in Scattering of Liquid Phantoms. Advances in Experimental Medicine and Biology, 1072:375-379.

Abstract

Several cerebral oximeters based on near-infrared spectroscopy (NIRS) are commercially available that determine tissue oxygen saturation (StO). One problem is an inconsistency of StO readings between different brands of instruments. Liquid blood phantoms mimicking optical properties of the neonatal head enable quantitative device comparisons. However, occasionally, the reduced scattering coefficient (μ') of these phantoms decreases over time. AIM To investigate whether this decrease in μ' affects the validity of comparison of these devices. StO was measured by several NIRS oximeters simultaneously on a phantom, which exhibited a particularly strong decrease in μ'. We found that a decrease in μ' by ≤16% from baseline led to deviations in StO of ≤3%.

Abstract

Several cerebral oximeters based on near-infrared spectroscopy (NIRS) are commercially available that determine tissue oxygen saturation (StO). One problem is an inconsistency of StO readings between different brands of instruments. Liquid blood phantoms mimicking optical properties of the neonatal head enable quantitative device comparisons. However, occasionally, the reduced scattering coefficient (μ') of these phantoms decreases over time. AIM To investigate whether this decrease in μ' affects the validity of comparison of these devices. StO was measured by several NIRS oximeters simultaneously on a phantom, which exhibited a particularly strong decrease in μ'. We found that a decrease in μ' by ≤16% from baseline led to deviations in StO of ≤3%.

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Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neonatology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2018
Deposited On:25 Oct 2018 10:03
Last Modified:24 Sep 2019 23:49
Publisher:Springer
ISSN:0065-2598
OA Status:Green
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1007/978-3-319-91287-5_60
PubMed ID:30178374

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