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A pilot study of total and allergen-specific IgE serum levels during anestrous, estrous and pregnancy in healthy female dogs


Tarpataki, N; Thuróczy, J; Fischer, Nina M; Jacquenet, S; Rostaher, Ana; Richard, C; Zwickl, L; Olivry, T; Favrot, Claude (2018). A pilot study of total and allergen-specific IgE serum levels during anestrous, estrous and pregnancy in healthy female dogs. Veterinary Dermatology:Epub ahead of print.

Abstract

BACKGROUND: Allergen-specific IgE serology is used for the determination of sensitization status in dogs with atopic dermatitis; the influence of the female reproductive cycle on the results of such methods has not been studied in dogs.
OBJECTIVES: To compare the total and allergen-specific IgE of healthy bitches during anestrous, estrous and pregnancy.
ANIMALS: Eight privately owned, healthy bitches.
METHODS: Total and allergen-specific IgE levels were determined in eight bitches at three different time-points of their reproductive cycle: anestrous, estrous and pregnancy.
RESULTS: Total IgE was significantly decreased (median: 74%) in female dogs during pregnancy when compared to anestrous. In 14 of 216 (6%), allergen-specific IgE test results were variably positive and negative at different stages of the reproductive cycle. This variation, however, was not related to changes in total serum IgE levels.
CONCLUSIONS: Total IgE serum levels are reduced during pregnancy in female dogs. However, results of one allergen-specific IgE test did not appear to be markedly altered by the reproductive cycle in healthy bitches.

Abstract

BACKGROUND: Allergen-specific IgE serology is used for the determination of sensitization status in dogs with atopic dermatitis; the influence of the female reproductive cycle on the results of such methods has not been studied in dogs.
OBJECTIVES: To compare the total and allergen-specific IgE of healthy bitches during anestrous, estrous and pregnancy.
ANIMALS: Eight privately owned, healthy bitches.
METHODS: Total and allergen-specific IgE levels were determined in eight bitches at three different time-points of their reproductive cycle: anestrous, estrous and pregnancy.
RESULTS: Total IgE was significantly decreased (median: 74%) in female dogs during pregnancy when compared to anestrous. In 14 of 216 (6%), allergen-specific IgE test results were variably positive and negative at different stages of the reproductive cycle. This variation, however, was not related to changes in total serum IgE levels.
CONCLUSIONS: Total IgE serum levels are reduced during pregnancy in female dogs. However, results of one allergen-specific IgE test did not appear to be markedly altered by the reproductive cycle in healthy bitches.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Department of Small Animals
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Language:English
Date:23 April 2018
Deposited On:10 Dec 2018 15:49
Last Modified:10 Dec 2018 15:49
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0959-4493
OA Status:Closed
Publisher DOI:https://doi.org/10.1111/vde.12544
PubMed ID:29687519

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