Navigation auf zora.uzh.ch

Search ZORA

ZORA (Zurich Open Repository and Archive)

Ultrasonographic evaluation of reticular motility in cows after administration of atropine, scopolamine and xylazine*

Braun, Ueli; Gansohr, B; Hässig, Michael (2002). Ultrasonographic evaluation of reticular motility in cows after administration of atropine, scopolamine and xylazine*. Journal of Veterinary Medicine Series A, 49(6):299-302.

Abstract

The goal of this study was to evaluate the effect of various dosages and routes of administration of atropine, scopolamine and xylazine on reticular motility in cows. Groups of five cows received atropine, scopolamine or xylazine at dosages varying from 0.01 to 0.20 mg/kg. The drugs were administered intramuscularly and intravenously; atropine was also given subcutaneously. A total of 17 trials, each using five cows, were carried out. Reticular motility was assessed for 3 min immediately prior to the administration of a drug and for 21 min after administration, and the latter period was divided into seven 3-min intervals. The motility was further assessed during 3-min periods every 10 min starting 28 min and ending 141 min after administration of a drug. During each 3-min interval, the number of reticular contractions or the occurrence of reticular atony was determined. Onset and duration of reticular atony were assessed. All three drugs inhibited reticular motility but onset varied with route of administration and dosage. As expected, the onset of reticular atony occurred most rapidly after intravenous administration of each drug, followed by intramuscular and subcutaneous administration. Reticular atony occurred 0-3.0 min after the intravenous administration of each drug and at all dosages except the lowest dosage of atropine. Atony lasted for 3-111 min. Reticular atony occurred 3-18 min and 9-15 min after intramuscular and subcutaneous administration, respectively. It lasted 32-108 min and 39-122 min for the intramuscular and subcutaneous routes, respectively. For each drug, higher dosages resulted in a more rapid onset and longer duration of reticular atony than did lower dosages. This study demonstrated that administration of atropine, scopolamine and xylazine results in reticular atony. Whether this has clinical relevance requires further investigation.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Department of Farm Animals
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Scopus Subject Areas:Health Sciences > Pathology and Forensic Medicine
Health Sciences > General Veterinary
Language:English
Date:1 August 2002
Deposited On:11 Dec 2018 12:05
Last Modified:20 Oct 2024 01:36
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0931-184X
OA Status:Closed
Publisher DOI:https://doi.org/10.1046/j.1439-0442.2002.00450.x

Metadata Export

Statistics

Citations

Dimensions.ai Metrics
17 citations in Web of Science®
20 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

0 downloads since deposited on 11 Dec 2018
0 downloads since 12 months

Authors, Affiliations, Collaborations

Similar Publications