Greenland’s peripheral glaciers and ice caps are key indicators of climate change in the Arctic, but quantitative observational data of their recent evolution are sparse. Three recently released high-resolution digital elevation models (DEMs)—AeroDEM (based on images from 1978 to 1987), ArcticDEM (2012–2015), and TanDEM-X (2010–2014)—provide the possibility to calculate elevation changes spanning almost four decades along the margins of the Greenland Ice Sheet. This study explores the potential of these DEMs by calculating elevation changes for the Holm Land Ice Cap (865 km2), northeast Greenland. Co-registration indicated no significant shifts between the DEMs but we encountered localized vertical offsets in AeroDEM. The data quality of ArcticDEM and TanDEM-X is high, but AeroDEM suffers from 19 percent low-quality data, which were treated as data voids. Applying two approaches to fill the data voids in the difference grid between ArcticDEM and AeroDEM, mean surface-elevation change over the Holm Land Ice Cap and a period of approximately 35 y is in the range of −8.30 ±0.30 m. Comparing ArcticDEM and
TanDEM-X reveals a glacier elevation difference of 2.54 m, which may be partly related to the different retrieval techniques (optical and SAR). Overall, the DEMs have good potential for large-scale and long-term assessment of geodetic glacier mass balance.