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Perioperative Endocarditis Management in a Patient with Homozygous Sickle Cell Disease

Gozdzik, Malgorzata; Mariotti, Sergio; Genoni, Michele; Zientara, Alicja (2019). Perioperative Endocarditis Management in a Patient with Homozygous Sickle Cell Disease. Thoracic and Cardiovascular Surgeon Reports, 8(1):e1-e4.

Abstract

Background  Homozygous sickle cell disease (SCD) compounded with bacterial endocarditis makes open-heart surgery a multidisciplinary challenge. Case description  A 45-year-old African male patient with homozygous SCD presented with right heart decompensation, tricuspid regurgitation, and endocarditis of the aortic valve. Blood coulters were positive for coagulase-negative staphylococci. An emergent double valve replacement was successfully performed involving a multidisciplinary team. Conclusion  Homozygous SCD is associated with an increased risk of preoperative vaso-occlusive complications. Surgery with cardiopulmonary bypass can be performed, if hypothermia, hypoxia, acidosis, or low-flows are being avoided. Due to the lack of data, the adequate approach is still intuitive and requires standardization.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiac Surgery
04 Faculty of Medicine > University Hospital Zurich > Institute of Anesthesiology
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:cardiopulmonary Bypass endocarditis hemofiltration sickle cell disease sickle crisis
Language:English
Date:January 2019
Deposited On:14 Mar 2019 11:59
Last Modified:20 Dec 2024 02:39
Publisher:Georg Thieme Verlag
ISSN:2194-7635
OA Status:Gold
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1055/s-0038-1676962
PubMed ID:30648104
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