Baruscotti, I; Gillespie, D G; Jackson, E K; Imthurn, B (2008). Estradiol induces mitogenesis in human progenitor endothelial cells (PECs) by upregulating cyclins and downregulating p21. In: 7th Day of Clinical Research, University Hospital Zurich, 27 March 2008 - 29 March 2008.
Circulating progenitor endothelial cells (PECs) play a critical role in repairing damaged endothelial layer. Since estradiol is vasoprotective (1), it may promote vascular endothelial recovery by inducing PEC-proliferation. Here we investigated the growth effects of estradiol on human PECs and the intracellular mechanisms involved.
Circulating progenitor endothelial cells (PECs) play a critical role in repairing damaged endothelial layer. Since estradiol is vasoprotective (1), it may promote vascular endothelial recovery by inducing PEC-proliferation. Here we investigated the growth effects of estradiol on human PECs and the intracellular mechanisms involved.
| Item Type: | Conference or Workshop Item (Other), refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Clinic for Reproductive Endocrinology |
| Dewey Decimal Classification: | 610 Medicine & health |
| Language: | German |
| Event End Date: | 29 March 2008 |
| Deposited On: | 24 Feb 2011 16:10 |
| Last Modified: | 18 Feb 2018 11:04 |
| OA Status: | Closed |
Baruscotti, I