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Electromagnetic fields and optomechanics in cancer diagnostics and treatment


Salari, Vahid; Barzanjeh, Shabir; Cifra, Michal; Simon, Christoph; Scholkmann, Felix; Alirezaei, Zahra; Tuszynski, Jack A (2018). Electromagnetic fields and optomechanics in cancer diagnostics and treatment. Frontiers in Bioscience, 23:1391-1406.

Abstract

In this paper, we discuss biological effects of electromagnetic (EM) fields in the context of cancer biology. In particular, we review the nanomechanical properties of microtubules (MTs), the latter being one of the most successful targets for cancer therapy. We propose an investigation on the coupling of electromagnetic radiation to mechanical vibrations of MTs as an important basis for biological and medical applications. In our opinion, optomechanical methods can accurately monitor and control the mechanical properties of isolated MTs in a liquid environment. Consequently, studying nanomechanical properties of MTs may give useful information for future applications to diagnostic and therapeutic technologies involving non-invasive externally applied physical fields. For example, electromagnetic fields or high intensity ultrasound can be used therapeutically avoiding harmful side effects of chemotherapeutic agents or classical radiation therapy.

Abstract

In this paper, we discuss biological effects of electromagnetic (EM) fields in the context of cancer biology. In particular, we review the nanomechanical properties of microtubules (MTs), the latter being one of the most successful targets for cancer therapy. We propose an investigation on the coupling of electromagnetic radiation to mechanical vibrations of MTs as an important basis for biological and medical applications. In our opinion, optomechanical methods can accurately monitor and control the mechanical properties of isolated MTs in a liquid environment. Consequently, studying nanomechanical properties of MTs may give useful information for future applications to diagnostic and therapeutic technologies involving non-invasive externally applied physical fields. For example, electromagnetic fields or high intensity ultrasound can be used therapeutically avoiding harmful side effects of chemotherapeutic agents or classical radiation therapy.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neonatology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1 March 2018
Deposited On:22 Feb 2019 11:04
Last Modified:30 Jan 2020 13:58
Publisher:Frontiers in Bioscience
ISSN:1093-4715
OA Status:Closed
Publisher DOI:https://doi.org/10.2741/4651
Official URL:https://www.bioscience.org/2018/v23/af/4651/fulltext.htm
PubMed ID:29293441

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