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Treatment of arterial thrombosis in children: Methods and mechanisms


Rizzi, Mattia; Albisetti, Manuela (2018). Treatment of arterial thrombosis in children: Methods and mechanisms. Thrombosis research, 169:113-119.

Abstract

Arterial thrombosis is increasingly recognized in children and is mostly related to the presence of an arterial catheter or an ischemic stroke. Treatment of children with arterial thrombosis varies widely and consists on the administration of the common available anticoagulant und antiplatelet drugs. No evidence-based guidelines are available so far to prefer one treatment approach to another. Data in adults indicate that understanding the pathomechanism and composition of arterial thrombosis is crucial for choosing the most efficient and safe antithrombotic drug. This review will briefly summarize new insights on the pathomechanism and composition of arterial thrombosis in adults and describe available antithrombotic treatment modalities currently used n children.

Abstract

Arterial thrombosis is increasingly recognized in children and is mostly related to the presence of an arterial catheter or an ischemic stroke. Treatment of children with arterial thrombosis varies widely and consists on the administration of the common available anticoagulant und antiplatelet drugs. No evidence-based guidelines are available so far to prefer one treatment approach to another. Data in adults indicate that understanding the pathomechanism and composition of arterial thrombosis is crucial for choosing the most efficient and safe antithrombotic drug. This review will briefly summarize new insights on the pathomechanism and composition of arterial thrombosis in adults and describe available antithrombotic treatment modalities currently used n children.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:September 2018
Deposited On:28 Feb 2019 16:26
Last Modified:28 Feb 2019 16:27
Publisher:Elsevier
ISSN:0049-3848
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.thromres.2018.07.013
PubMed ID:30032038

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