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Cardiac- versus diaphragm-based respiratory navigation for proton spectroscopy of the heart


Gastl, Mareike; Peereboom, Sophie M; Fuetterer, Maximilian; Boenner, Florian; Kelm, Malte; Manka, Robert; Kozerke, Sebastian (2019). Cardiac- versus diaphragm-based respiratory navigation for proton spectroscopy of the heart. Magma, 32(2):259-268.

Abstract

OBJECTIVES To study inter-individual differences of the relation between diaphragm and heart motion, the objective of the present study was to implement respiratory navigation on the heart and compare it against the established method of navigator gating on the diaphragm for single-voxel cardiac H-MRS.
MATERIALS AND METHODS H-MRS was performed on a 1.5T system in 19 healthy volunteers of mixed age (range 24-75 years). Spectra were recorded in a 6-8 ml voxel in the ventricular septum using a PRESS (point-resolved spectroscopy) sequence and ECG gating. Water-unsuppressed data acquired with pencil beam navigation on the heart were compared to data with navigation on the diaphragm. Water-suppressed data were obtained to assess triglyceride-to-water ratios.
RESULTS Water phase and amplitude fluctuations for cardiac versus diaphragm navigation did not reveal significant differences. Both navigator positions provided comparable triglyceride-to-water ratios and gating efficiencies (coefficient of variation (CoV) 7.0%). The cardiac navigator showed a good reproducibility (CoV 5.2%).
DISCUSSION Respiratory navigation on the heart does not convey an advantage over diaphragm-based navigator gating for cardiac H-MRS, but also no disadvantage. Consequently, cardiac and diaphragm respiratory navigation may be used interchangeably.

Abstract

OBJECTIVES To study inter-individual differences of the relation between diaphragm and heart motion, the objective of the present study was to implement respiratory navigation on the heart and compare it against the established method of navigator gating on the diaphragm for single-voxel cardiac H-MRS.
MATERIALS AND METHODS H-MRS was performed on a 1.5T system in 19 healthy volunteers of mixed age (range 24-75 years). Spectra were recorded in a 6-8 ml voxel in the ventricular septum using a PRESS (point-resolved spectroscopy) sequence and ECG gating. Water-unsuppressed data acquired with pencil beam navigation on the heart were compared to data with navigation on the diaphragm. Water-suppressed data were obtained to assess triglyceride-to-water ratios.
RESULTS Water phase and amplitude fluctuations for cardiac versus diaphragm navigation did not reveal significant differences. Both navigator positions provided comparable triglyceride-to-water ratios and gating efficiencies (coefficient of variation (CoV) 7.0%). The cardiac navigator showed a good reproducibility (CoV 5.2%).
DISCUSSION Respiratory navigation on the heart does not convey an advantage over diaphragm-based navigator gating for cardiac H-MRS, but also no disadvantage. Consequently, cardiac and diaphragm respiratory navigation may be used interchangeably.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1 April 2019
Deposited On:01 Mar 2019 08:40
Last Modified:20 Mar 2019 02:06
Publisher:Springer
ISSN:0968-5243
OA Status:Closed
Publisher DOI:https://doi.org/10.1007/s10334-018-0711-y
PubMed ID:30377860

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