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Direct hyperpolarization of micro- and nanodiamonds for bioimaging applications – Considerations on particle size, functionalization and polarization loss


Kwiatkowski, Grzegorz; Jähnig, Fabian; Steinhauser, Jonas; Wespi, Patrick; Ernst, Matthias; Kozerke, Sebastian (2018). Direct hyperpolarization of micro- and nanodiamonds for bioimaging applications – Considerations on particle size, functionalization and polarization loss. Journal of Magnetic Resonance, 286:42-51.

Abstract

Due to the inherently long relaxation time of 13C spins in diamond, the nuclear polarization enhancement obtained with dynamic nuclear polarization can be preserved for a time on the order of about one hour, opening up an opportunity to use diamonds as a new class of long-lived contrast agents. The present communication explores the feasibility of using 13C spins in directly hyperpolarized diamonds for MR imaging including considerations for potential in vivo applications.

Abstract

Due to the inherently long relaxation time of 13C spins in diamond, the nuclear polarization enhancement obtained with dynamic nuclear polarization can be preserved for a time on the order of about one hour, opening up an opportunity to use diamonds as a new class of long-lived contrast agents. The present communication explores the feasibility of using 13C spins in directly hyperpolarized diamonds for MR imaging including considerations for potential in vivo applications.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Biomedical Engineering
Dewey Decimal Classification:170 Ethics
610 Medicine & health
Uncontrolled Keywords:Nuclear and High Energy Physics, Biophysics, Biochemistry, Condensed Matter Physics
Language:English
Date:1 January 2018
Deposited On:06 Mar 2019 13:17
Last Modified:25 Sep 2019 00:23
Publisher:Elsevier
ISSN:1090-7807
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.jmr.2017.11.007
PubMed ID:29183003

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