Kwiatkowski, Grzegorz; Jähnig, Fabian; Steinhauser, Jonas; Wespi, Patrick; Ernst, Matthias; Kozerke, Sebastian (2018). Direct hyperpolarization of micro- and nanodiamonds for bioimaging applications – Considerations on particle size, functionalization and polarization loss. Journal of Magnetic Resonance, 286:42-51.
Due to the inherently long relaxation time of 13C spins in diamond, the nuclear polarization enhancement obtained with dynamic nuclear polarization can be preserved for a time on the order of about one hour, opening up an opportunity to use diamonds as a new class of long-lived contrast agents. The present communication explores the feasibility of using 13C spins in directly hyperpolarized diamonds for MR imaging including considerations for potential in vivo applications.
Due to the inherently long relaxation time of 13C spins in diamond, the nuclear polarization enhancement obtained with dynamic nuclear polarization can be preserved for a time on the order of about one hour, opening up an opportunity to use diamonds as a new class of long-lived contrast agents. The present communication explores the feasibility of using 13C spins in directly hyperpolarized diamonds for MR imaging including considerations for potential in vivo applications.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Institute of Biomedical Engineering |
| Dewey Decimal Classification: | 170 Ethics
610 Medicine & health |
| Scopus Subject Areas: | Life Sciences > Biophysics
Life Sciences > Biochemistry Physical Sciences > Nuclear and High Energy Physics Physical Sciences > Condensed Matter Physics |
| Uncontrolled Keywords: | Nuclear and High Energy Physics, Biophysics, Biochemistry, Condensed Matter Physics |
| Language: | English |
| Date: | 1 January 2018 |
| Deposited On: | 06 Mar 2019 13:17 |
| Last Modified: | 29 Jul 2020 10:02 |
| Publisher: | Elsevier |
| ISSN: | 1090-7807 |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1016/j.jmr.2017.11.007 |
| PubMed ID: | 29183003 |
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Kwiatkowski, Grzegorz