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Total Cerebrovascular Blood Flow and Whole Brain Perfusion in Children Sedated Using Propofol With or Without Ketamine at Induction: An Investigation With 2D-Cine PC and ASL


Makki, Malek I; O'Gorman Tuura, Ruth L; Buhler, Philip; Baledent, Olivier; Kellenberger, Christian J; Sabandal, Carola; Weiss, Markus; Scheer, Ianina; Schmitz, Achim (2019). Total Cerebrovascular Blood Flow and Whole Brain Perfusion in Children Sedated Using Propofol With or Without Ketamine at Induction: An Investigation With 2D-Cine PC and ASL. Journal of Magnetic Resonance Imaging (JMRI), 50(5):1433-1440.

Abstract

BACKGROUND
Multiple sedation regimes may be used to facilitate pediatric MRI scans. These regimes might affect cerebral blood flow and hemodynamics to varying degrees, particularly in children who may be vulnerable to anesthetic side effects.
PURPOSE
To compare the effects of propofol monosedation solely (Pm group) vs. a combination of propofol and ketamine (KP group) on brain hemodynamics and perfusion.

Abstract

BACKGROUND
Multiple sedation regimes may be used to facilitate pediatric MRI scans. These regimes might affect cerebral blood flow and hemodynamics to varying degrees, particularly in children who may be vulnerable to anesthetic side effects.
PURPOSE
To compare the effects of propofol monosedation solely (Pm group) vs. a combination of propofol and ketamine (KP group) on brain hemodynamics and perfusion.

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Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1 November 2019
Deposited On:10 Jan 2020 08:40
Last Modified:31 Jan 2020 12:52
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:1053-1807
OA Status:Closed
Publisher DOI:https://doi.org/10.1002/jmri.26725
PubMed ID:30892782

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