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Cell-Based Therapies for the Treatment of Fractures


Borrelli, Joseph; Della Rocca, Gregory J; Schneider, Prism; Pape, Hans-Christoph; Cinelli, Paolo; Weil, Yoram; Khoury, Amal; Liebergall, Meir; Watson, Tracy (2019). Cell-Based Therapies for the Treatment of Fractures. Journal of Orthopaedic Trauma, 33 Suppl:S39-S43.

Abstract

Ongoing studies investigating fracture healing have uncovered and allowed investigators to gain a better understanding of where the variety of cells, which participate in this process, originate, and how they communicate as well as how they can be enhanced to successfully heal a fracture when the process has slowed or failed completely. This brief review will highlight some of the recent findings regarding the role the immune system in fracture healing and how these cells communicate with each other during the healing process. In addition, two 2 methods that have recently been shown to be promising techniques in supporting fracture when it stalls or reversing the process, when the fracture has failed to heal, will also be described.

Abstract

Ongoing studies investigating fracture healing have uncovered and allowed investigators to gain a better understanding of where the variety of cells, which participate in this process, originate, and how they communicate as well as how they can be enhanced to successfully heal a fracture when the process has slowed or failed completely. This brief review will highlight some of the recent findings regarding the role the immune system in fracture healing and how these cells communicate with each other during the healing process. In addition, two 2 methods that have recently been shown to be promising techniques in supporting fracture when it stalls or reversing the process, when the fracture has failed to heal, will also be described.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Department of Trauma Surgery
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:June 2019
Deposited On:22 May 2019 13:14
Last Modified:25 Sep 2019 00:35
Publisher:Lippincott Williams & Wilkins
ISSN:0890-5339
OA Status:Closed
Publisher DOI:https://doi.org/10.1097/BOT.0000000000001478
PubMed ID:31083148

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Embargo till: 2020-06-01