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Physiological and emotional effects of pentatonic live music played for preterm neonates and their mothers in the Newborn Intensive Care Unit: A randomized controlled trial


Ranger, A; Helmert, E; Bott, T S; Ostermann, T; Als, H; Bassler, D; Hautzinger, M; Vagedes, J (2018). Physiological and emotional effects of pentatonic live music played for preterm neonates and their mothers in the Newborn Intensive Care Unit: A randomized controlled trial. Complementary Therapies in Medicine, 41:240-246.

Abstract

OBJECTIVE
Despite attempts to increase calmness in the Newborn Intensive Care Unit (NICU), preterm neonates still experience stress. The question arises how to further promote the infants' wellbeing. Therefore, the immediate effects of pentatonic live music on preterm infants and their mothers were examined.
DESIGN AND METHODS
In a two-centre randomized controlled trial with crossover design preterm infants were exposed sequentially to two conditions: live pentatonic harp music (LPHM) used in Anthroposophic Medicine or standard care. The order of the conditions was randomized within each subject. The primary outcome was change of the number of oxygen desaturations < 90%/h, whereas secondary outcomes were: heart rate, respiratory rate, oxygen saturation, heart rate variability (HRV), the perfusion index, pulse-transit-time and maternal anxiety and others not reported on in this article.
RESULTS
21 preterm infants were randomized (14 girls), mean gestational age at measurement 35 + 0 weeks (SD 1 week). The primary outcome parameter showed no significant changes. Regarding the secondary outcomes the comparison of the pre-post-differences between the conditions showed significant effects for the HRV parameters pNN (ΔpNN = 1.46%, z = -2.47, p =  .001) and SDNN (ΔSDNN=-0.06 ms, z = -2.25, p =  .002). The music intervention significantly increased the values of pNN (Mdn 1.2% vs. 2.6%, p =  0.04) and marginally those of SDNN (Mdn 31.7 ms vs. 36.4 ms, p =  0.05). No changes were found in the other parameters.
CONCLUSIONS
While the use of music in the NICU had no effect on the number of oxygen desaturations, it increased two HRV parameters indicative of infants' parasympathetic tone.

Abstract

OBJECTIVE
Despite attempts to increase calmness in the Newborn Intensive Care Unit (NICU), preterm neonates still experience stress. The question arises how to further promote the infants' wellbeing. Therefore, the immediate effects of pentatonic live music on preterm infants and their mothers were examined.
DESIGN AND METHODS
In a two-centre randomized controlled trial with crossover design preterm infants were exposed sequentially to two conditions: live pentatonic harp music (LPHM) used in Anthroposophic Medicine or standard care. The order of the conditions was randomized within each subject. The primary outcome was change of the number of oxygen desaturations < 90%/h, whereas secondary outcomes were: heart rate, respiratory rate, oxygen saturation, heart rate variability (HRV), the perfusion index, pulse-transit-time and maternal anxiety and others not reported on in this article.
RESULTS
21 preterm infants were randomized (14 girls), mean gestational age at measurement 35 + 0 weeks (SD 1 week). The primary outcome parameter showed no significant changes. Regarding the secondary outcomes the comparison of the pre-post-differences between the conditions showed significant effects for the HRV parameters pNN (ΔpNN = 1.46%, z = -2.47, p =  .001) and SDNN (ΔSDNN=-0.06 ms, z = -2.25, p =  .002). The music intervention significantly increased the values of pNN (Mdn 1.2% vs. 2.6%, p =  0.04) and marginally those of SDNN (Mdn 31.7 ms vs. 36.4 ms, p =  0.05). No changes were found in the other parameters.
CONCLUSIONS
While the use of music in the NICU had no effect on the number of oxygen desaturations, it increased two HRV parameters indicative of infants' parasympathetic tone.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neonatology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:December 2018
Deposited On:31 Jul 2019 10:31
Last Modified:25 Sep 2019 00:38
Publisher:Elsevier
ISSN:0965-2299
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.ctim.2018.07.009
PubMed ID:30477847

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