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Editorial: Physical Virology and the Nature of Virus Infections


Greber, Urs F (2019). Editorial: Physical Virology and the Nature of Virus Infections. In: Greber, Urs F. Physical Virology. Basel, Switzerland: Springer, online.

Abstract

Virus particles, ‘virions’, range in size from nano-scale to micro-scale. They have many different shapes and are composed of proteins, sugars, nucleic acids, lipids, water and solutes. Virions are autonomous entities and affect all forms of life in a parasitic relationship. They infect prokaryotic and eukaryotic cells. The physical properties of virions are tuned to the way they interact with cells. When virions interact with cells, they gain huge complexity and give rise to an infected cell, also known as ‘virus’. Virion–cell interactions entail the processes of entry, replication and assembly, as well as egress from the infected cell. Collectively, these steps can result in progeny virions, which is a productive infection, or in silencing of the virus, an abortive or latent infection. This book explores facets of the physical nature of virions and viruses and the impact of mechanical properties on infection processes at the cellular and subcellular levels.

Abstract

Virus particles, ‘virions’, range in size from nano-scale to micro-scale. They have many different shapes and are composed of proteins, sugars, nucleic acids, lipids, water and solutes. Virions are autonomous entities and affect all forms of life in a parasitic relationship. They infect prokaryotic and eukaryotic cells. The physical properties of virions are tuned to the way they interact with cells. When virions interact with cells, they gain huge complexity and give rise to an infected cell, also known as ‘virus’. Virion–cell interactions entail the processes of entry, replication and assembly, as well as egress from the infected cell. Collectively, these steps can result in progeny virions, which is a productive infection, or in silencing of the virus, an abortive or latent infection. This book explores facets of the physical nature of virions and viruses and the impact of mechanical properties on infection processes at the cellular and subcellular levels.

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Additional indexing

Item Type:Book Section, refereed, further contribution
Communities & Collections:07 Faculty of Science > Institute of Molecular Life Sciences
Dewey Decimal Classification:570 Life sciences; biology
Scopus Subject Areas:Life Sciences > General Biochemistry, Genetics and Molecular Biology
Language:English
Date:1 January 2019
Deposited On:08 Aug 2019 08:37
Last Modified:29 Jul 2020 11:03
Publisher:Springer
Series Name:Advances in Experimental Medicine and Biology
Number:1140
ISSN:0065-2598
ISBN:9783030147402
Additional Information:This is a post-peer-review, pre-copyedit version of an article published in Advances in Experimental Medicine and Biology. The final authenticated version is available online at: https://doi.org/10.1007/978-3-030-14741-9_1
OA Status:Green
Publisher DOI:https://doi.org/10.1007/978-3-030-14741-9_1
Official URL:https://link.springer.com/book/10.1007/978-3-030-14741-9
PubMed ID:31317493

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