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Induction of labor and postpartum blood loss


Brun, Romana; Spoerri, Emilian; Schäffer, Leonhard; Zimmermann, Roland; Haslinger, Christian (2019). Induction of labor and postpartum blood loss. BMC Pregnancy and Childbirth, 19(1):265.

Abstract

BACKGROUND
To analyze blood loss after delivery in women with induction of labor compared to women with spontaneous onset of labor.
METHODS
In this secondary analysis of a prospective cohort study investigating postpartum hemorrhage, 965 deliveries were analyzed including 380 women with induction of labor (39%) between 2015 and 2016. Primary outcome parameters were rate of postpartum hemorrhage, estimated blood loss and post-partum decrease in hemoglobin.
RESULTS
Rates of postpartum hemorrhage and estimated blood loss were not significantly different in women with induction of labor. Women with induction of labor had a significantly reduced decrease in hemoglobin after delivery. In the multivariate linear regression analysis, induction of labor remained associated with reduced decrease in hemoglobin. Secondary maternal and neonatal outcomes were unaffected.
CONCLUSIONS
Induction of labor is not associated with increased blood loss after delivery and should not be regarded as a risk factor for postpartum hemorrhage.

Abstract

BACKGROUND
To analyze blood loss after delivery in women with induction of labor compared to women with spontaneous onset of labor.
METHODS
In this secondary analysis of a prospective cohort study investigating postpartum hemorrhage, 965 deliveries were analyzed including 380 women with induction of labor (39%) between 2015 and 2016. Primary outcome parameters were rate of postpartum hemorrhage, estimated blood loss and post-partum decrease in hemoglobin.
RESULTS
Rates of postpartum hemorrhage and estimated blood loss were not significantly different in women with induction of labor. Women with induction of labor had a significantly reduced decrease in hemoglobin after delivery. In the multivariate linear regression analysis, induction of labor remained associated with reduced decrease in hemoglobin. Secondary maternal and neonatal outcomes were unaffected.
CONCLUSIONS
Induction of labor is not associated with increased blood loss after delivery and should not be regarded as a risk factor for postpartum hemorrhage.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Obstetrics
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:25 July 2019
Deposited On:16 Aug 2019 13:18
Last Modified:01 Oct 2019 11:38
Publisher:BioMed Central
ISSN:1471-2393
OA Status:Gold
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1186/s12884-019-2410-8
PubMed ID:31345178

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