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Soft biomimetic nanoconfinement promotes amorphous water over ice


Salvati Manni, Livia; Assenza, S; Duss, Michael; Vallooran, J J; Juranyi, F; Jurt, Simon; Zerbe, Oliver; Landau, Ehud M; Mezzenga, Raffaele (2019). Soft biomimetic nanoconfinement promotes amorphous water over ice. Nature Nanotechnology, 14:609-615.

Abstract

Water is a ubiquitous liquid with unique physicochemical properties, whose nature has shaped our planet and life as we know it. Water in restricted geometries has different properties than in bulk. Confinement can prevent low-temperature crystalliza- tion of the molecules into a hexagonal structure and thus create a state of amorphous water. To understand the survival of life at subzero temperatures, it is essential to elucidate this behaviour in the presence of nanoconfining lipidic membranes. Here we introduce a family of synthetic lipids with designed cyclopropyl modifications in the hydrophobic chains that exhibit unique liquid-crystalline behaviour at low temperature, which enables the maintenance of amorphous water down to ~10 K due to nano- confinement. The combination of experiments and molecular dynamics simulations unveils a complex lipid–water phase dia- gram in which bicontinuous cubic and lamellar liquid crystalline phases that contain subzero liquid, glassy or ice water emerge as a competition between the two components, each pushing towards its thermodynamically favoured state.

Abstract

Water is a ubiquitous liquid with unique physicochemical properties, whose nature has shaped our planet and life as we know it. Water in restricted geometries has different properties than in bulk. Confinement can prevent low-temperature crystalliza- tion of the molecules into a hexagonal structure and thus create a state of amorphous water. To understand the survival of life at subzero temperatures, it is essential to elucidate this behaviour in the presence of nanoconfining lipidic membranes. Here we introduce a family of synthetic lipids with designed cyclopropyl modifications in the hydrophobic chains that exhibit unique liquid-crystalline behaviour at low temperature, which enables the maintenance of amorphous water down to ~10 K due to nano- confinement. The combination of experiments and molecular dynamics simulations unveils a complex lipid–water phase dia- gram in which bicontinuous cubic and lamellar liquid crystalline phases that contain subzero liquid, glassy or ice water emerge as a competition between the two components, each pushing towards its thermodynamically favoured state.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Department of Chemistry
Dewey Decimal Classification:540 Chemistry
Scopus Subject Areas:Physical Sciences > Bioengineering
Physical Sciences > Atomic and Molecular Physics, and Optics
Physical Sciences > Biomedical Engineering
Physical Sciences > General Materials Science
Physical Sciences > Condensed Matter Physics
Physical Sciences > Electrical and Electronic Engineering
Language:English
Date:2019
Deposited On:30 Aug 2019 10:12
Last Modified:29 Jul 2020 11:15
Publisher:Nature Publishing Group
ISSN:1748-3387
OA Status:Closed
Publisher DOI:https://doi.org/10.1038/s41565-019-0415-0

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