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Tantal (alveolengängige Fraktion) [MAK Value Documentation in German language, 2017]


Hartwig, Andrea; MAK Commission; et al; Arand, Michael (2017). Tantal (alveolengängige Fraktion) [MAK Value Documentation in German language, 2017]. The MAK Collection for Occupational Health and Safety, 2(1):126-134.

Abstract

Tantalum is a biopersistent granular dust of a high density. Tantalum is not systemically distributed and accumulates only locally in the lungs. On the basis of current knowledge it cannot be estimated to what extent the high density of the tantalum particles has an influence on the burden of macrophages and the transport of the particles by the macrophages. Therefore, a MAK value in analogy to the biopersistent granular dusts cannot be established. Consequently, the respirable fraction of tantalum dust is classified in Carcinogen Category 3R and remains a candidate for Carcinogen Category 4.

Since no MAK value can be established, neither a peak limitation category nor a pregnancy risk group can be determined for tantalum. Tantalum is not designated with either “Sa” or “Sh” or “H”.

Abstract

Tantalum is a biopersistent granular dust of a high density. Tantalum is not systemically distributed and accumulates only locally in the lungs. On the basis of current knowledge it cannot be estimated to what extent the high density of the tantalum particles has an influence on the burden of macrophages and the transport of the particles by the macrophages. Therefore, a MAK value in analogy to the biopersistent granular dusts cannot be established. Consequently, the respirable fraction of tantalum dust is classified in Carcinogen Category 3R and remains a candidate for Carcinogen Category 4.

Since no MAK value can be established, neither a peak limitation category nor a pregnancy risk group can be determined for tantalum. Tantalum is not designated with either “Sa” or “Sh” or “H”.

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Additional indexing

Item Type:Journal Article, not_refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Pharmacology and Toxicology
07 Faculty of Science > Institute of Pharmacology and Toxicology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:German
Date:26 January 2017
Deposited On:18 Oct 2019 08:16
Last Modified:18 Oct 2019 08:17
Publisher:Wiley-VCH Verlag
ISSN:2509-2383
ISBN:9783527600410
OA Status:Closed
Publisher DOI:https://doi.org/10.1002/3527600418.mb744025stad0062

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