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Addendum zu Brommethan (Methylbromid) [BAT Value Documentation in German language, 2016]


Hallier, E; Müller, M; Drexler, H; Hartwig, A; MAK Commission; et al; Arand, Michael (2016). Addendum zu Brommethan (Methylbromid) [BAT Value Documentation in German language, 2016]. The MAK Collection for Occupational Health and Safety, 1(3):2075-2079.

Abstract

Brommethan (Methyl bromide): Addendum BAT value documentation (2016)

The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the “Biologischer Leitwert” (BLW) for methyl bromide, using bromide in serum/plasma to characterize the internal exposure. The critical effect of methyl bromide is a high acute and chronic neurotoxicity. It can pass through the skin so that biological monitoring is highly recommended.

On the basis of results of a human study the occurrence of abnormal findings in the EEG is comparable for unexposed persons and persons with exposure to methyl bromide in concentrations below 12 mg bromide/l plasma. Thus the BLW value of 12 mg bromide/l plasma or serum was confirmed. The sampling time is at the end of exposure/shift after several previous shifts.

Abstract

Brommethan (Methyl bromide): Addendum BAT value documentation (2016)

The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the “Biologischer Leitwert” (BLW) for methyl bromide, using bromide in serum/plasma to characterize the internal exposure. The critical effect of methyl bromide is a high acute and chronic neurotoxicity. It can pass through the skin so that biological monitoring is highly recommended.

On the basis of results of a human study the occurrence of abnormal findings in the EEG is comparable for unexposed persons and persons with exposure to methyl bromide in concentrations below 12 mg bromide/l plasma. Thus the BLW value of 12 mg bromide/l plasma or serum was confirmed. The sampling time is at the end of exposure/shift after several previous shifts.

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Additional indexing

Item Type:Journal Article, not_refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Pharmacology and Toxicology
07 Faculty of Science > Institute of Pharmacology and Toxicology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:German
Date:25 July 2016
Deposited On:18 Oct 2019 08:38
Last Modified:18 Oct 2019 08:41
Publisher:Wiley-VCH Verlag
ISSN:2509-2383
ISBN:9783527600410
OA Status:Closed
Publisher DOI:https://doi.org/10.1002/3527600418.bb7483d0022

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