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Iod und anorganische Iodide [BAT Value Documentation in German language, 2016]


Nasterlack, M; Drexler, H; Hartwig, A; MAK Commission; et al; Arand, Michael (2016). Iod und anorganische Iodide [BAT Value Documentation in German language, 2016]. The MAK Collection for Occupational Health and Safety, 1(4):2686-2696.

Abstract

The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated iodine and inorganic iodides. Available publications are described in detail.
There is no reproducible quantitative relation between iodine exposure, absorption and resulting body burden. The association between iodine absorption and the incidence of thyroid dysfunction seems to be U‐shaped. Therefore, no sharp boundary can be drawn between iodine oversupply and iodine deficiency relating to individual health. No harmless range could be indicated, so a BAT value (biological tolerance value) for iodine and inorganic iodides could not be derived.

There are major regional differences due to different geological deposits of iodine, different concentrations of iodine in drinking water, iodine‐containing aerosols and nutritional habits. Furthermore, there is a high variability in the urinary analysis. Therefore, a BAR (“Biologischer Arbeitsstoff‐Referenzwert”) for iodine and inorganic iodides could not be derived.

Abstract

The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated iodine and inorganic iodides. Available publications are described in detail.
There is no reproducible quantitative relation between iodine exposure, absorption and resulting body burden. The association between iodine absorption and the incidence of thyroid dysfunction seems to be U‐shaped. Therefore, no sharp boundary can be drawn between iodine oversupply and iodine deficiency relating to individual health. No harmless range could be indicated, so a BAT value (biological tolerance value) for iodine and inorganic iodides could not be derived.

There are major regional differences due to different geological deposits of iodine, different concentrations of iodine in drinking water, iodine‐containing aerosols and nutritional habits. Furthermore, there is a high variability in the urinary analysis. Therefore, a BAR (“Biologischer Arbeitsstoff‐Referenzwert”) for iodine and inorganic iodides could not be derived.

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Additional indexing

Item Type:Journal Article, not_refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Pharmacology and Toxicology
07 Faculty of Science > Institute of Pharmacology and Toxicology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:German
Date:26 October 2016
Deposited On:18 Oct 2019 08:35
Last Modified:18 Oct 2019 08:50
Publisher:Wiley-VCH Verlag
ISSN:2509-2383
ISBN:9783527600410
OA Status:Closed
Publisher DOI:https://doi.org/10.1002/3527600418.bb755356d0022

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