The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the maximum concentration at the workplace (MAK value) of triethanolamine [102‐71‐6].
Critical effect is the inflammation of the larynx observed in a 28‐day study in rats with a BMDL05 of 14 mg/m3. An analysis of the studies with monoethanolamine, diethanolamine and 7 other studies with substances that cause inflammation of the larynx shows that the NOAEC in subchronic or chronic studies is lower than in subacute studies. Therefore, for a chronic exposure to triethanolamine at the workplace a decrease of the NOAEC cannot be excluded and the MAK value is lowered to 1 mg/m3 for the inhalable fraction.
Triethanolamine remains assigned to Peak Limitation Category I for locally acting substances. An excursion factor of 1 is set by analogy with the other ethanolamines.