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The 1-Minute Sit-to-Stand Test in Lung Transplant Candidates: An Easy-to-Use Alternative to the 6-Minute Walk Test?


Kohlbrenner, Dario; Benden, Christian; Radtke, Thomas (2020). The 1-Minute Sit-to-Stand Test in Lung Transplant Candidates: An Easy-to-Use Alternative to the 6-Minute Walk Test? Respiratory Care, 65(4):437-443.

Abstract

BACKGROUND
The 6-min walk test (6MWT) is a well-established functional exercise capacity test in lung transplant candidates. This study aimed to investigate the construct validity of the 1-min sit-to-stand test (1-min STS) as a marker of exercise capacity and knee extensor strength in lung transplantation candidates.
METHODS
We retrospectively analyzed data from consecutive subjects referred for lung transplantation evaluation to our institution between 2015 and 2018.
RESULTS
38 subjects were included. We found strong correlations between the normalized 1-min STS and 6MWT (r = 0.79, P < .001) and moderate correlations between 1-min STS and knee extensor strength (r = 0.53, P = .001) and between 6MWT and knee extensor strength (r = 0.44, P = .008). The 1-min STS elicited greater dyspnea (P = .008) and lower oxygen desaturation compared to the 6MWT (P < .001). The 1-min STS is a valid functional exercise capacity test in lung transplantation candidates. Our study may stimulate future research, including a head-to-head comparison between the 6MWT and 1-min STS in a large patient cohort including post-lung transplantation-monitoring.
CONCLUSIONS
Due to its ease of application, clinical practitioners may consider using the 1-min STS in situations when the 6MWT cannot be performed.

Abstract

BACKGROUND
The 6-min walk test (6MWT) is a well-established functional exercise capacity test in lung transplant candidates. This study aimed to investigate the construct validity of the 1-min sit-to-stand test (1-min STS) as a marker of exercise capacity and knee extensor strength in lung transplantation candidates.
METHODS
We retrospectively analyzed data from consecutive subjects referred for lung transplantation evaluation to our institution between 2015 and 2018.
RESULTS
38 subjects were included. We found strong correlations between the normalized 1-min STS and 6MWT (r = 0.79, P < .001) and moderate correlations between 1-min STS and knee extensor strength (r = 0.53, P = .001) and between 6MWT and knee extensor strength (r = 0.44, P = .008). The 1-min STS elicited greater dyspnea (P = .008) and lower oxygen desaturation compared to the 6MWT (P < .001). The 1-min STS is a valid functional exercise capacity test in lung transplantation candidates. Our study may stimulate future research, including a head-to-head comparison between the 6MWT and 1-min STS in a large patient cohort including post-lung transplantation-monitoring.
CONCLUSIONS
Due to its ease of application, clinical practitioners may consider using the 1-min STS in situations when the 6MWT cannot be performed.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
04 Faculty of Medicine > University Hospital Zurich > Clinic for Pneumology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1 April 2020
Deposited On:05 Dec 2019 11:33
Last Modified:27 Mar 2020 02:03
Publisher:Daedalus Enterprises, Inc.
ISSN:0020-1324
OA Status:Closed
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.4187/respcare.07124
PubMed ID:31641072

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