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Clinical Applications of Spectral CT


Euler, André; Schindera, Sebastian T (2020). Clinical Applications of Spectral CT. In: Samei, Ehsan; Pelc, Norbert J. Computed Tomography : Approaches, Applications, and Operations. Cham: Springer, 243-268.

Abstract

Dual-energy computed tomography (DECT) has evolved from a research tool to an established clinical imaging modality since its first commercial introduction in the mid-2000s. The possibility to characterize the composition of different human tissues and the quantification of certain materials like iodine, calcium, or fat have shown clinical benefit for various body regions. Virtual monoenergetic imaging (VMI) and multi-material decomposition (MMD) imaging (see Chap. 12) are the most popular and investigated applications of DECT that can be used to improve detection and conspicuity of disease as well as objective and subjective image quality. Furthermore, virtual non-contrast (VNC) imaging can reduce the radiation exposure to the patient by omitting the need for a conventional non-contrast CT scan. In this chapter we review clinically established applications of DECT for the main body regions from head to toe. Moreover, we highlight interesting experimental and preclinical research topics that may become clinically available in the future. Concluding this chapter, we discuss the potential pitfalls associated with DECT.

Abstract

Dual-energy computed tomography (DECT) has evolved from a research tool to an established clinical imaging modality since its first commercial introduction in the mid-2000s. The possibility to characterize the composition of different human tissues and the quantification of certain materials like iodine, calcium, or fat have shown clinical benefit for various body regions. Virtual monoenergetic imaging (VMI) and multi-material decomposition (MMD) imaging (see Chap. 12) are the most popular and investigated applications of DECT that can be used to improve detection and conspicuity of disease as well as objective and subjective image quality. Furthermore, virtual non-contrast (VNC) imaging can reduce the radiation exposure to the patient by omitting the need for a conventional non-contrast CT scan. In this chapter we review clinically established applications of DECT for the main body regions from head to toe. Moreover, we highlight interesting experimental and preclinical research topics that may become clinically available in the future. Concluding this chapter, we discuss the potential pitfalls associated with DECT.

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Additional indexing

Item Type:Book Section, not_refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Diagnostic and Interventional Radiology
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Epidemiology
Health Sciences > Medicine (miscellaneous)
Social Sciences & Humanities > Education
Physical Sciences > Modeling and Simulation
Language:English
Date:1 January 2020
Deposited On:08 Jan 2020 08:36
Last Modified:22 May 2020 08:37
Publisher:Springer
ISBN:978-3-030-26956-2
OA Status:Closed
Publisher DOI:https://doi.org/10.1007/978-3-030-26957-9_13
Related URLs:https://doi.org/10.1007/978-3-030-26957-9 (Publisher)

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