Header

UZH-Logo

Maintenance Infos

Actimetry in infant sleep research: an approach to facilitate comparability


Schoch, Sarah F; Jenni, Oskar G; Kohler, Malcolm; Kurth, Salome (2019). Actimetry in infant sleep research: an approach to facilitate comparability. Sleep, 42(7):online.

Abstract

Study Objectives
Only standardized objective assessments reliably capture the large variability of sleep behavior in infancy, which is the most pronounced throughout the human lifespan. This is important for clinical practice as well as basic research. Actimetry is a cost-efficient method to objectively estimate infant sleep/wake behavior from limb movements. Nevertheless, the standardization of actimetry-based sleep/wake measures is limited by two factors: the use of different computational approaches and the bias towards measuring only nighttime sleep—neglecting ~20 % of sleep infants obtain during daytime. Thus, we evaluate the comparability of two commonly used actimetry algorithms in infants and propose adjustments to increase comparability.
Methods
We used actimetry in 50 infants for 10 continuous days at ages 3, 6, and 12 months in a longitudinal approach. We analyzed the infants’ sleep/wake behaviors by applying two algorithms: Sadeh and Oakley/Respironics. We compared minute-by-minute agreement and Kappa between the two algorithms, as well as the algorithms with sleep/wake measures from a comprehensive 24-hour parent-reported diary.
Results
Agreement between uncorrected algorithms was moderate (77%–84%). By introducing a six-step adjustment, we increased agreement between algorithms (96%–97%) and with the diary. This decreased the difference in estimated sleep behaviors, e.g. Total Sleep Duration from 4.5 to 0.2 hours.
Conclusions
These adjustments enhance comparability between infant actimetry studies and the inclusion of parent-reported diaries allows the integration of daytime sleep. Objectively assessed infant sleep that is comparable across different studies supports the establishment of normative developmental trajectories and clinical cutoffs.

Abstract

Study Objectives
Only standardized objective assessments reliably capture the large variability of sleep behavior in infancy, which is the most pronounced throughout the human lifespan. This is important for clinical practice as well as basic research. Actimetry is a cost-efficient method to objectively estimate infant sleep/wake behavior from limb movements. Nevertheless, the standardization of actimetry-based sleep/wake measures is limited by two factors: the use of different computational approaches and the bias towards measuring only nighttime sleep—neglecting ~20 % of sleep infants obtain during daytime. Thus, we evaluate the comparability of two commonly used actimetry algorithms in infants and propose adjustments to increase comparability.
Methods
We used actimetry in 50 infants for 10 continuous days at ages 3, 6, and 12 months in a longitudinal approach. We analyzed the infants’ sleep/wake behaviors by applying two algorithms: Sadeh and Oakley/Respironics. We compared minute-by-minute agreement and Kappa between the two algorithms, as well as the algorithms with sleep/wake measures from a comprehensive 24-hour parent-reported diary.
Results
Agreement between uncorrected algorithms was moderate (77%–84%). By introducing a six-step adjustment, we increased agreement between algorithms (96%–97%) and with the diary. This decreased the difference in estimated sleep behaviors, e.g. Total Sleep Duration from 4.5 to 0.2 hours.
Conclusions
These adjustments enhance comparability between infant actimetry studies and the inclusion of parent-reported diaries allows the integration of daytime sleep. Objectively assessed infant sleep that is comparable across different studies supports the establishment of normative developmental trajectories and clinical cutoffs.

Statistics

Citations

Dimensions.ai Metrics
3 citations in Web of Science®
1 citation in Scopus®
Google Scholar™

Altmetrics

Downloads

5 downloads since deposited on 13 Jan 2020
5 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
04 Faculty of Medicine > University Hospital Zurich > Clinic for Pneumology
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Neurology (clinical)
Health Sciences > Physiology (medical)
Uncontrolled Keywords:Physiology (medical), Clinical Neurology
Language:English
Date:8 July 2019
Deposited On:13 Jan 2020 16:27
Last Modified:29 Jul 2020 12:32
Publisher:American Academy of Sleep Medicine
ISSN:0161-8105
OA Status:Hybrid
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1093/sleep/zsz083
PubMed ID:30941431

Download

Hybrid Open Access

Download PDF  'Actimetry in infant sleep research: an approach to facilitate comparability'.
Preview
Content: Published Version
Filetype: PDF
Size: 10MB
View at publisher
Licence: Creative Commons: Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)