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A rare cause of a cholestatic jaundice in a North African teenager


Schreiner, Philipp; Stieger, Bruno; McLin, Valérie; Rougemont, Anne‐Laure; Keitel, Verena; Dröge, Carola; Müllhaupt, Beat (2019). A rare cause of a cholestatic jaundice in a North African teenager. Liver International, 39(11):2036-2041.

Abstract

We report an unusual case of intermittent episodes of cholestasis in a young patient. The cholestatic attacks were preceded in each case by an infection and subsequent antibiotic therapies. After ruling out many possible causes of cholestatic hepatitis, the differential diagnoses were a benign recurrent intrahepatic cholestasis or a drug-induced liver injury. We discuss here the diagnostic approach and interpretation of the genetic analysis.

Abstract

We report an unusual case of intermittent episodes of cholestasis in a young patient. The cholestatic attacks were preceded in each case by an infection and subsequent antibiotic therapies. After ruling out many possible causes of cholestatic hepatitis, the differential diagnoses were a benign recurrent intrahepatic cholestasis or a drug-induced liver injury. We discuss here the diagnostic approach and interpretation of the genetic analysis.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Clinical Pharmacology and Toxicology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Gastroenterology and Hepatology
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:Hepatology
Language:English
Date:1 November 2019
Deposited On:16 Jan 2020 08:42
Last Modified:16 Jan 2020 08:42
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:1478-3223
OA Status:Closed
Publisher DOI:https://doi.org/10.1111/liv.14122
PubMed ID:31021034

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Embargo till: 2020-04-25