There are few reports describing suture periostitis (SP) in horses. This case series outlines the clinical, radiographic and histologic features of SP and compares various types of treatment in 15 horses presented to the Equine Clinic, Vetsuisse-Faculty, University of Zurich. Overall, the incidence of horses with SP presented to our clinic was low, and clinical signs were similar to those previously reported. Radiography was used to diagnose SP, but computed tomography was the imaging modality of choice for determining the extent of the bony changes and the suture lines affected. Horses that underwent surgical stabilization had more rapid resolution of signs than those treated conservatively or not treated at all.