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Spectral analysis of the sleep electroencephalogram during adolescence


Jenni, Oskar G; Carskadon, Mary A (2004). Spectral analysis of the sleep electroencephalogram during adolescence. Sleep, 27(4):774-83.

Abstract

OBJECTIVES

To describe developmental changes of the human sleep electroencephalogram (EEG) during adolescence using EEG spectral analysis and specifically to compare the nocturnal dynamics of slow-wave activity (EEG spectral power 0.6-4.6 Hz, a marker for sleep homeostatic pressure) in prepubertal and mature adolescents.

DESIGN After 10 nights on a fixed 10-hour sleep schedule without daytime naps, participants were studied during a 10-hour baseline night.

SETTING Data were collected in a 4-bed sleep research laboratory.

PARTICIPANTS

Eight prepubertal children (pubertal stage Tanner 1; mean age 11.3 years, SD +/- 1.2, 4 boys) and 8 mature adolescents (Tanner 5; mean age 14.1 years, +/- 1.3, 3 boys).

INTERVENTIONS Not applicable.

MEASUREMENTS

All-night polysomnography was performed. Sleep stages were scored according to conventional criteria. EEG power spectra (of derivation C3/A2) were calculated using a fast Fourier transform routine.

RESULTS

A reduction of non-rapid eye movement (NREM) sleep stage 4 (by 40.1%) and greater amounts of stage 2 sleep (19.7%) were found in mature compared to prepubertal adolescents. NREM sleep EEG power was lower in the frequency ranges < 7 Hz, 11.8 to 12.6 Hz, and 16.2 to 16.8 Hz in mature adolescents. A reduction of rapid eye movement sleep spectral power was present in the frequency ranges < 8.6 Hz and 9.6 to 15 Hz for mature compared to prepubertal adolescents. Slow-wave activity showed identical dynamics within individual NREM sleep episodes and across the night in both developmental groups.

CONCLUSIONS

The homeostatic recuperative drive during sleep remains unchanged across puberty. The decline of slow-wave sleep during adolescence may reflect developmental changes of the brain rather than changes of sleep regulatory processes.

Abstract

OBJECTIVES

To describe developmental changes of the human sleep electroencephalogram (EEG) during adolescence using EEG spectral analysis and specifically to compare the nocturnal dynamics of slow-wave activity (EEG spectral power 0.6-4.6 Hz, a marker for sleep homeostatic pressure) in prepubertal and mature adolescents.

DESIGN After 10 nights on a fixed 10-hour sleep schedule without daytime naps, participants were studied during a 10-hour baseline night.

SETTING Data were collected in a 4-bed sleep research laboratory.

PARTICIPANTS

Eight prepubertal children (pubertal stage Tanner 1; mean age 11.3 years, SD +/- 1.2, 4 boys) and 8 mature adolescents (Tanner 5; mean age 14.1 years, +/- 1.3, 3 boys).

INTERVENTIONS Not applicable.

MEASUREMENTS

All-night polysomnography was performed. Sleep stages were scored according to conventional criteria. EEG power spectra (of derivation C3/A2) were calculated using a fast Fourier transform routine.

RESULTS

A reduction of non-rapid eye movement (NREM) sleep stage 4 (by 40.1%) and greater amounts of stage 2 sleep (19.7%) were found in mature compared to prepubertal adolescents. NREM sleep EEG power was lower in the frequency ranges < 7 Hz, 11.8 to 12.6 Hz, and 16.2 to 16.8 Hz in mature adolescents. A reduction of rapid eye movement sleep spectral power was present in the frequency ranges < 8.6 Hz and 9.6 to 15 Hz for mature compared to prepubertal adolescents. Slow-wave activity showed identical dynamics within individual NREM sleep episodes and across the night in both developmental groups.

CONCLUSIONS

The homeostatic recuperative drive during sleep remains unchanged across puberty. The decline of slow-wave sleep during adolescence may reflect developmental changes of the brain rather than changes of sleep regulatory processes.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Neurology (clinical)
Health Sciences > Physiology (medical)
Language:English
Date:15 June 2004
Deposited On:20 Feb 2020 08:58
Last Modified:22 Apr 2020 22:45
Publisher:American Academy of Sleep Medicine
ISSN:0161-8105
OA Status:Closed
PubMed ID:15283014

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