Header

UZH-Logo

Maintenance Infos

Epileptic High-frequency Oscillations in Scalp Electroencephalography


Shibata, Takashi; Kobayashi, Katsuhiro (2018). Epileptic High-frequency Oscillations in Scalp Electroencephalography. Acta Medica Okayama, 72(4):325-329.

Abstract

Electroencephalography (EEG) examines the functional state of the brain. High-frequency oscillations (HFOs) in the ripple (80-200/250 Hz) and fast ripple (200/250-500/600 Hz) bands have recently been attracting attention, and their recording has been enabled by advancements in digital EEG techniques. The detection of HFOs was previously limited to intracranial EEG, but fast oscillations (FOs) in the gamma (40-80 Hz) and ripple bands can now be detected over the scalp. HFOs and FOs have been shown to be related to epileptogenicity in intracranial EEG and scalp EEG, respectively. A large number of FOs are found in the scalp EEGs of pediatric patients with various epileptic encephalopathies, particularly West syndrome. FOs are suggested to be a biomarker of the epileptogenic cortical region in epilepsy surgery. FOs are detectable even in patients with idiopathic focal epilepsies, including benign epilepsy with centrotemporal spikes and Panayiotopoulos syndrome, who are not generally candidates for operation. The detection of HFOs and FOs may provide clues to the pathophysiology of epilepsy and the relationship between HFOs and cognitive dysfunction.

Abstract

Electroencephalography (EEG) examines the functional state of the brain. High-frequency oscillations (HFOs) in the ripple (80-200/250 Hz) and fast ripple (200/250-500/600 Hz) bands have recently been attracting attention, and their recording has been enabled by advancements in digital EEG techniques. The detection of HFOs was previously limited to intracranial EEG, but fast oscillations (FOs) in the gamma (40-80 Hz) and ripple bands can now be detected over the scalp. HFOs and FOs have been shown to be related to epileptogenicity in intracranial EEG and scalp EEG, respectively. A large number of FOs are found in the scalp EEGs of pediatric patients with various epileptic encephalopathies, particularly West syndrome. FOs are suggested to be a biomarker of the epileptogenic cortical region in epilepsy surgery. FOs are detectable even in patients with idiopathic focal epilepsies, including benign epilepsy with centrotemporal spikes and Panayiotopoulos syndrome, who are not generally candidates for operation. The detection of HFOs and FOs may provide clues to the pathophysiology of epilepsy and the relationship between HFOs and cognitive dysfunction.

Statistics

Citations

Altmetrics

Downloads

2 downloads since deposited on 06 Feb 2020
2 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Clinic for Surgery
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:August 2018
Deposited On:06 Feb 2020 14:01
Last Modified:06 Feb 2020 14:01
Publisher:Okayama University Medical School
ISSN:0386-300X
OA Status:Green
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.18926/AMO/56166
PubMed ID:30140078

Download

Green Open Access

Download PDF  'Epileptic High-frequency Oscillations in Scalp Electroencephalography'.
Preview
Content: Published Version
Filetype: PDF
Size: 2MB
View at publisher