Traffic Medicine is one of the Swiss legal entities that contribute to minimizing traffic casualties. But has pertaining Swiss legislation adequately incorporated developments in medicine, science, society and politics to attain this goal? Moreover, is the field in general sufficiently prepared and agile to react timely to heralding mega-trends such as legalization and medical use of cannabis, automation and overaging of drivers? Our objective is to reflect roughly a decade of measures affecting Swiss traffic medicine. With a focus on medically relevant measures, we review origin, implementation and –wherever already ascertainable –resulting effects, both from the practical and scientific perspective of a traffic medicine expert.