Wagner, Karoline; Preiswerk, Benjamin; Keller, Peter M; Schulthess, Bettina (2019). Defining threshold values in microscopic examination and qPCR for optimal performance of line probe assays for resistance detection in Mycobacterium tuberculosis complex. Diagnostic Microbiology and Infectious Disease, 95(2):159-161.
Line probe assays enable rapid detection of drug-resistant Mycobacterium tuberculosis directly from clinical specimens. This study shows that defining threshold values in microscopic examination or PCR detection of M. tuberculosis optimizes line probe assay efficiency, thereby avoiding costs and loss of time due to unnecessary molecular testing.
Line probe assays enable rapid detection of drug-resistant Mycobacterium tuberculosis directly from clinical specimens. This study shows that defining threshold values in microscopic examination or PCR detection of M. tuberculosis optimizes line probe assay efficiency, thereby avoiding costs and loss of time due to unnecessary molecular testing.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Institute of Medical Microbiology |
| Dewey Decimal Classification: | 570 Life sciences; biology
610 Medicine & health |
| Scopus Subject Areas: | Health Sciences > Microbiology (medical)
Health Sciences > Infectious Diseases |
| Language: | English |
| Date: | October 2019 |
| Deposited On: | 13 Feb 2020 15:55 |
| Last Modified: | 27 Jan 2022 01:17 |
| Publisher: | Elsevier |
| ISSN: | 0732-8893 |
| OA Status: | Closed |
| Publisher DOI: | https://doi.org/10.1016/j.diagmicrobio.2019.06.001 |
| PubMed ID: | 31279584 |
Wagner, Karoline