Header

UZH-Logo

Maintenance Infos

Defining threshold values in microscopic examination and qPCR for optimal performance of line probe assays for resistance detection in Mycobacterium tuberculosis complex


Wagner, Karoline; Preiswerk, Benjamin; Keller, Peter M; Schulthess, Bettina (2019). Defining threshold values in microscopic examination and qPCR for optimal performance of line probe assays for resistance detection in Mycobacterium tuberculosis complex. Diagnostic Microbiology and Infectious Disease, 95(2):159-161.

Abstract

Line probe assays enable rapid detection of drug-resistant Mycobacterium tuberculosis directly from clinical specimens. This study shows that defining threshold values in microscopic examination or PCR detection of M. tuberculosis optimizes line probe assay efficiency, thereby avoiding costs and loss of time due to unnecessary molecular testing.

Abstract

Line probe assays enable rapid detection of drug-resistant Mycobacterium tuberculosis directly from clinical specimens. This study shows that defining threshold values in microscopic examination or PCR detection of M. tuberculosis optimizes line probe assay efficiency, thereby avoiding costs and loss of time due to unnecessary molecular testing.

Statistics

Citations

Altmetrics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Medical Microbiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Scopus Subject Areas:Health Sciences > Microbiology (medical)
Health Sciences > Infectious Diseases
Language:English
Date:October 2019
Deposited On:13 Feb 2020 15:55
Last Modified:29 Jul 2020 14:22
Publisher:Elsevier
ISSN:0732-8893
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.diagmicrobio.2019.06.001
PubMed ID:31279584

Download

Full text not available from this repository.
View at publisher

Get full-text in a library