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Invasive meningococcal and pneumococcal disease in Switzerland: cost?utility analysis of different vaccine strategies


Jaccard Ruedin, Helene; Ess, S; Zimmermann, H P; Szucs, Thomas (2003). Invasive meningococcal and pneumococcal disease in Switzerland: cost?utility analysis of different vaccine strategies. Vaccine, 21(27-30):4145-4152.

Abstract

We performed a cost-utility analysis for various vaccination strategies against meningococcal and pneumococcal diseases (MenC or MenC/PCV-9) in Switzerland. The analysis compared the current recommendations of vaccinating only children with medical risks to the introduction of the vaccination with either the MenC or the MenC/PCV-9 vaccine, administered at 12 or 2, 4 and 6 months of age, into the existing immunisation programme. For a birth cohort of 80,000 children and assuming a vaccine coverage of 80%, the introduction of a generalised vaccination would be cost-effective. The strategy using three doses of MenC/PCV-9 would achieve the highest health benefit, with 440 quality-adjusted life years (QALYs) gained at costs of 34,000 per QALY.

Abstract

We performed a cost-utility analysis for various vaccination strategies against meningococcal and pneumococcal diseases (MenC or MenC/PCV-9) in Switzerland. The analysis compared the current recommendations of vaccinating only children with medical risks to the introduction of the vaccination with either the MenC or the MenC/PCV-9 vaccine, administered at 12 or 2, 4 and 6 months of age, into the existing immunisation programme. For a birth cohort of 80,000 children and assuming a vaccine coverage of 80%, the introduction of a generalised vaccination would be cost-effective. The strategy using three doses of MenC/PCV-9 would achieve the highest health benefit, with 440 quality-adjusted life years (QALYs) gained at costs of 34,000 per QALY.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Life Sciences > Molecular Medicine
Life Sciences > General Immunology and Microbiology
Health Sciences > General Veterinary
Health Sciences > Public Health, Environmental and Occupational Health
Health Sciences > Infectious Diseases
Language:English
Date:1 October 2003
Deposited On:24 Feb 2020 16:59
Last Modified:31 Jul 2020 03:49
Publisher:Elsevier
ISSN:0264-410X
Additional Information:zugleich MPH-Diplomarbeit
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/s0264-410x(03)00562-0
PubMed ID:14505894

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