Header

UZH-Logo

Maintenance Infos

Disinfecting noncritical medical equipment-Effectiveness of hydrogen peroxide dry mist as an adjunctive method


Amodio, Enrica; Kuster, Stefan P; Garzoni, Christian; Zinkernagel, Annelies S; Sax, Hugo; Wolfensberger, Aline (2020). Disinfecting noncritical medical equipment-Effectiveness of hydrogen peroxide dry mist as an adjunctive method. American Journal of Infection Control, 48(8):897-902.

Abstract

BACKGROUND: Manual disinfection of medical devices is prone to failure. Disinfection by aerosolized hydrogen peroxide might be a promising adjunctive method. We aimed to assess effectiveness of dry mist of hydrogen peroxide (HPDM) on noncritical medical equipment.
METHODS: One cycle of HPDM was applied on a convenience sample of 16 different types of "ready to use" noncritical medical devices in a closed, but nonsealed room. Of every object, 2 adjacent areas with assumed similar bacterial burden were swabbed before and after HPDM deployment, respectively. After culturing, colony forming units (CFU) were counted, and bacterial burden per cm$^{2}$ calculated.
RESULTS: Of 160 objects included in the study, 36 (23%) showed a CFU-count of zero both before and after HPDM use. A decrease from a median of 0.14 CFU/cm$^{2}$ (range: 0.00-125.00/cm$^{2}$) to a median of 0.00 CFU/cm$^{2}$ (range: 0.00-4.00/cm$^{2}$) (P < .001) was observed. The bacterial burden was reduced by more than 90% in 45% (95% CI: 37-53) of objects. No pathogenic bacteria were identified.
DISCUSSION: HPDM reduced bacterial burden on noncritical medical items. Since cleanliness of the included "ready to use" objects was high and no pathogens were found before nebulization, the HPDM device did not increase patient safety in this setting.
CONCLUSION: HPDM nebulization can be a useful nonmanual adjunctive disinfection method in high-risk settings.

Abstract

BACKGROUND: Manual disinfection of medical devices is prone to failure. Disinfection by aerosolized hydrogen peroxide might be a promising adjunctive method. We aimed to assess effectiveness of dry mist of hydrogen peroxide (HPDM) on noncritical medical equipment.
METHODS: One cycle of HPDM was applied on a convenience sample of 16 different types of "ready to use" noncritical medical devices in a closed, but nonsealed room. Of every object, 2 adjacent areas with assumed similar bacterial burden were swabbed before and after HPDM deployment, respectively. After culturing, colony forming units (CFU) were counted, and bacterial burden per cm$^{2}$ calculated.
RESULTS: Of 160 objects included in the study, 36 (23%) showed a CFU-count of zero both before and after HPDM use. A decrease from a median of 0.14 CFU/cm$^{2}$ (range: 0.00-125.00/cm$^{2}$) to a median of 0.00 CFU/cm$^{2}$ (range: 0.00-4.00/cm$^{2}$) (P < .001) was observed. The bacterial burden was reduced by more than 90% in 45% (95% CI: 37-53) of objects. No pathogenic bacteria were identified.
DISCUSSION: HPDM reduced bacterial burden on noncritical medical items. Since cleanliness of the included "ready to use" objects was high and no pathogens were found before nebulization, the HPDM device did not increase patient safety in this setting.
CONCLUSION: HPDM nebulization can be a useful nonmanual adjunctive disinfection method in high-risk settings.

Statistics

Citations

Dimensions.ai Metrics
4 citations in Web of Science®
5 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

18 downloads since deposited on 26 Oct 2020
9 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Infectious Diseases
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Epidemiology
Health Sciences > Health Policy
Health Sciences > Public Health, Environmental and Occupational Health
Health Sciences > Infectious Diseases
Language:English
Date:August 2020
Deposited On:26 Oct 2020 17:58
Last Modified:23 Jun 2024 01:44
Publisher:Elsevier
ISSN:0196-6553
OA Status:Hybrid
Publisher DOI:https://doi.org/10.1016/j.ajic.2020.05.016
PubMed ID:32464292
  • Content: Published Version
  • Language: English
  • Licence: Creative Commons: Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)