Spiritual care has gained importance in various areas of the healthcare system in recent years. Treatment models try to integrate spiritual concerns and needs and strengthen inter-professional cooperation in this context. How this is practised in Switzerland has not yet been comprehensively evaluated. The aim of our study was to examine to what extent and in what ways health professionals consider spiritual issues to be already taken into account or are willing to do so in their professional practice. A total of 196 people took part in the online survey. The results show that many healthcare professionals in acute settings regard spiritual care as an important part of interdisciplinary care, even if it is not yet well established. End-of-life situations are most strongly associated with spiritual care. The study provides an insight into the state of development of professional spiritual care in Switzerland and forms a basis for further research in and development of interprofessional spiritual care in acute settings.