InSAR time series of surface deformation from 16 yr of Envisat (2003-2011) and Sentinel-1 (2014-2019) ESA satellite radar measurements have been constructed to characterise spatial and temporal dynamics of ground deformation over an 80,000 km2 area in the permafrost of the northeastern Tibetan Plateau. The regional deformation maps encompass various types of periglacial landforms and show that seasonal thaw effects are controlled by the sediment type and local topography. High seasonal ground movements are concentrated on shallow slopes and poor-drainage areas in unconsolidated, frost-susceptible and fine-grained sediments within glacier outwash plains, braided stream plains, alluvial deposits or floodplains. Fast subsidence due to thaw settlement takes place during June/July while frost heave is intense during December/January when two-sided freezing of pore water under pressure causes prolonged ice segregation near the permafrost table. The analysis reveals pervasive subsidence of the ground of up to ∼2 cm/yr, and increasing by a factor of 2 to 5 from 2003 to today, in high-relief and well-drained areas. The findings suggest that seasonal thaw increasingly affects ice-rich layers at the permafrost table, as well as high-rates of widespread mass movements of non-consolidated sediments, the latter amplified by an increase of effects from frost heave/thaw settlement.