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Functional imaging of the piriform cortex in focal epilepsy


Koepp, Matthias; Galovic, Marian (2020). Functional imaging of the piriform cortex in focal epilepsy. Experimental Neurology, 330:113305.

Abstract

Experiments in animal models have identified specific brain regions such as the deep anterior piriform cortex as important for controlling the initiation or propagation of both generalized and focal seizure activity. However, there is little experimental evidence to translate these observations to the control of focal seizures in humans. Here, we summarize findings from different hemodynamic and neurotransmitter functional imaging studies in groups of patients with focal epilepsies arising from different cortical locations in support of a common area of brain dysfunction in focal epilepsies.

Abstract

Experiments in animal models have identified specific brain regions such as the deep anterior piriform cortex as important for controlling the initiation or propagation of both generalized and focal seizure activity. However, there is little experimental evidence to translate these observations to the control of focal seizures in humans. Here, we summarize findings from different hemodynamic and neurotransmitter functional imaging studies in groups of patients with focal epilepsies arising from different cortical locations in support of a common area of brain dysfunction in focal epilepsies.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurology
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Life Sciences > Neurology
Life Sciences > Developmental Neuroscience
Language:English
Date:August 2020
Deposited On:17 Dec 2020 12:53
Last Modified:18 Dec 2020 21:00
Publisher:Elsevier
ISSN:0014-4886
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.expneurol.2020.113305
PubMed ID:32278645

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Content: Accepted Version
Filetype: PDF - Registered users only until 1 August 2021
Size: 537kB
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Embargo till: 2021-08-01