The current Covid-19 pandemic has brought back memories of past epidemics. Pharaonic Egypt has often been associated with epidemics and disasters through the ten plagues of the Bible. The study examines which epidemics and serious diseases can be effectively proven for Ancient Egypt in mummies and historical source texts. The biblical plagues cannot be proven because there is no agreement on the dating of the Exodus or the Exodus is a conglomeration of memories of different events. Other diseases such as malaria and schistosomiasis have been proven for ancient Egypt, while polio and smallpox are still uncertain. From the time of the middle 18th dynasty there are indications of a bubonic disease, but its exact nature cannot be extracted from source texts or mummies, as they are too vague.