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Skipping adolescence to become super-inflammatory monocytes


Becher, Burkhard; De Feo, Donatella; Amorim, Ana; Greter, Melanie (2020). Skipping adolescence to become super-inflammatory monocytes. Nature Immunology, 21(5):491-492.

Abstract

Single-cell RNA-sequencing of myeloid cells during neuroinflammation identifies a new population of pathogenic Cxcl10-expressing phagocytes, which develop independently of Ly6Chi monocytes but derive from early myeloid precursors shaped by the inflamed tissue microenvironment.

Abstract

Single-cell RNA-sequencing of myeloid cells during neuroinflammation identifies a new population of pathogenic Cxcl10-expressing phagocytes, which develop independently of Ly6Chi monocytes but derive from early myeloid precursors shaped by the inflamed tissue microenvironment.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Institute of Experimental Immunology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Scopus Subject Areas:Health Sciences > Immunology and Allergy
Life Sciences > Immunology
Uncontrolled Keywords:Immunology
Language:English
Date:1 May 2020
Deposited On:31 Mar 2022 11:17
Last Modified:25 Mar 2024 02:46
Publisher:Nature Publishing Group
ISSN:1529-2908
OA Status:Closed
Publisher DOI:https://doi.org/10.1038/s41590-020-0652-2
PubMed ID:32313243
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