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Temporal trends in cardiovascular risk factors prevalence in patients with myocardial infarction


Cimci, Murat; Witassek, Fabienne; Radovanovic, Dragana; Rickli, Hans; Pedrazzini, Giovanni B; Erne, Paul; Müller, Olivier; Eberli, Franz R; Roffi, Marco (2020). Temporal trends in cardiovascular risk factors prevalence in patients with myocardial infarction. European Journal of Clinical Investigation:Epub ahead of print.

Abstract

INTRODUCTION AND OBJECTIVES

Little is known about changes in cardiovascular risk factors (CVRF) profile over time in patients presenting with acute myocardial infarction (AMI).

METHODS

We assessed changes in age and CVRF profile in consecutive AMI patients enrolled in the Swiss nationwide AMIS Plus registry between January 1, 1997 and December 31, 2018.

RESULTS

A total of 57,995 AMI patients were included in the analysis. Mean age at presentation was 71.5±11.3 years for women and 63.9±12.8 years for men and did not change over time. Overall, the mean (standard deviation) number of CVRF increased from 1.76 (1.07) in 1997/98 to 2.26 (1.10) in 2017/18 in men (P$_{trend}$ <0.001) while the corresponding rates in females were 1.83 (1.11) and 2.24 (1.08) (P$_{trend}$ <0.001). In terms of active smoking, no significant trend was detected for males while there was a significant increase in females (p<0.001). As a result, the gap in smoking rates between men and women presenting with AMI decreased from 19.9% (45.3% vs. 25.4%) in 1997/98 to 7.9% (41.2% vs. 33.3%) in 2017/18. Reassuring was the stability in terms of diabetes prevalence for both genders. Obesity was more prevalent over time in men while the prevalence of hypertension and dyslipidemia increased in both genders.

CONCLUSION

Among patients with AMI in Switzerland over two decades, age at presentation remained stable while the mean number of CVRF increased in both men and women. Striking was the increase in the prevalence of smoking in women, leading to a reduction of the gender gap over time.

Abstract

INTRODUCTION AND OBJECTIVES

Little is known about changes in cardiovascular risk factors (CVRF) profile over time in patients presenting with acute myocardial infarction (AMI).

METHODS

We assessed changes in age and CVRF profile in consecutive AMI patients enrolled in the Swiss nationwide AMIS Plus registry between January 1, 1997 and December 31, 2018.

RESULTS

A total of 57,995 AMI patients were included in the analysis. Mean age at presentation was 71.5±11.3 years for women and 63.9±12.8 years for men and did not change over time. Overall, the mean (standard deviation) number of CVRF increased from 1.76 (1.07) in 1997/98 to 2.26 (1.10) in 2017/18 in men (P$_{trend}$ <0.001) while the corresponding rates in females were 1.83 (1.11) and 2.24 (1.08) (P$_{trend}$ <0.001). In terms of active smoking, no significant trend was detected for males while there was a significant increase in females (p<0.001). As a result, the gap in smoking rates between men and women presenting with AMI decreased from 19.9% (45.3% vs. 25.4%) in 1997/98 to 7.9% (41.2% vs. 33.3%) in 2017/18. Reassuring was the stability in terms of diabetes prevalence for both genders. Obesity was more prevalent over time in men while the prevalence of hypertension and dyslipidemia increased in both genders.

CONCLUSION

Among patients with AMI in Switzerland over two decades, age at presentation remained stable while the mean number of CVRF increased in both men and women. Striking was the increase in the prevalence of smoking in women, leading to a reduction of the gender gap over time.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:30 November 2020
Deposited On:27 Jan 2021 12:33
Last Modified:27 Jan 2021 12:34
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0014-2972
OA Status:Closed
Publisher DOI:https://doi.org/10.1111/eci.13466
PubMed ID:33258133

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