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Implementierung der Behandlung durch enzymatisches Debridement bei Verbrennungen – Ergebnisse eines interprofessionellen, deutschsprachigen Expertenworkshops


Ziegler, Benjamin; Corterier, Cord; Kremer, Thomas; Lumenta, David B; Plock, Jan A; Richter, Sandy; Sander, Frank; Schiefer, Jennifer L; Siegwart, Laura C; Stauder, Martin; Wallner, Christoph; Wiechmann, Dirk; Hirche, Christoph (2020). Implementierung der Behandlung durch enzymatisches Debridement bei Verbrennungen – Ergebnisse eines interprofessionellen, deutschsprachigen Expertenworkshops. Handchirurgie, Mikrochirurgie, Plastische Chirurgie:Epub ahead of print.

Abstract

Introduction: Since its introduction in 2013 Bromelain-based Enzymatic Debridement (ED) is increasingly used in burn centers. Published evidence shows its efficiency in eschar removal as well as a superiority in blood loss and necessity of further surgical procedures compared to standard-of-care. While the procedure is safe and shows reliable results in experienced hands, some practical and logistical issues must be challenged that are not described sufficiently in available literature.

Method: A multi-professional panel, consisting of experienced users of ED from German-speaking burn units has been invited to an expert workshop. Topics concerning indication, definition of treatment pathways, practical issues, post-treatment and handling of complications have been coordinated in advance to allow discussion during the workshop.

Results: To each topic practical recommendations were developed and consented. Summarizing key messages have been additionally highlighted. They aim on helping to achieve optimal results after establishing the technique by new users as well as optimizing results by experienced users. Amongst others, the resulting recommendations deal with indications for ED beyond the classic domain, different treatment pathways depending on burn depth and primary result after ED with adapted post-treatment, management of treatment failure and implementation of infrastructural conditions.

Discussion: While efficiency of ED as well as superiority in some aspects of treatment of burn wounds could be shown in available literature, user-oriented recommendations for practical implementation are scarce. Although the recommendations and experts opinions published here are only partly evidenced based, they are still based on the pooled experienced of the panelists that easily outnumbers the cases published in literature so far and allow valuable support for a successful implementation of the technique.

Abstract

Introduction: Since its introduction in 2013 Bromelain-based Enzymatic Debridement (ED) is increasingly used in burn centers. Published evidence shows its efficiency in eschar removal as well as a superiority in blood loss and necessity of further surgical procedures compared to standard-of-care. While the procedure is safe and shows reliable results in experienced hands, some practical and logistical issues must be challenged that are not described sufficiently in available literature.

Method: A multi-professional panel, consisting of experienced users of ED from German-speaking burn units has been invited to an expert workshop. Topics concerning indication, definition of treatment pathways, practical issues, post-treatment and handling of complications have been coordinated in advance to allow discussion during the workshop.

Results: To each topic practical recommendations were developed and consented. Summarizing key messages have been additionally highlighted. They aim on helping to achieve optimal results after establishing the technique by new users as well as optimizing results by experienced users. Amongst others, the resulting recommendations deal with indications for ED beyond the classic domain, different treatment pathways depending on burn depth and primary result after ED with adapted post-treatment, management of treatment failure and implementation of infrastructural conditions.

Discussion: While efficiency of ED as well as superiority in some aspects of treatment of burn wounds could be shown in available literature, user-oriented recommendations for practical implementation are scarce. Although the recommendations and experts opinions published here are only partly evidenced based, they are still based on the pooled experienced of the panelists that easily outnumbers the cases published in literature so far and allow valuable support for a successful implementation of the technique.

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Additional indexing

Other titles:Implementation of treatment by enzymatic debridement in burns: results of an interprofessional German-speaking expert workshop
Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Reconstructive Surgery
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:14 December 2020
Deposited On:29 Jan 2021 10:53
Last Modified:29 Jan 2021 10:54
Publisher:Georg Thieme Verlag
ISSN:0722-1819
OA Status:Closed
Publisher DOI:https://doi.org/10.1055/a-1319-7566
PubMed ID:33316827

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