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A call for randomization in clinical trials of liver machine perfusion preservation


Martins, Paulo N; Clavien, Pierre‐Allain; Jalan, Rajiv; Ghinolfi, Davide (2021). A call for randomization in clinical trials of liver machine perfusion preservation. Hepatology, 73(6):2586-2591.

Abstract

Liver transplantation is a lifesaving operation for patients with advanced liver failure. Although mortality from liver disease continues to increase, the number of available grafts remain relatively unchanged, leading to the death of about 15-30% patients on the waiting list. Therefore, transplant teams have resorted to using marginal organs with often poorer outcomes.

Abstract

Liver transplantation is a lifesaving operation for patients with advanced liver failure. Although mortality from liver disease continues to increase, the number of available grafts remain relatively unchanged, leading to the death of about 15-30% patients on the waiting list. Therefore, transplant teams have resorted to using marginal organs with often poorer outcomes.

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Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Visceral and Transplantation Surgery
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Health Sciences > Hepatology
Uncontrolled Keywords:Hepatology
Language:English
Date:1 June 2021
Deposited On:08 Feb 2021 16:01
Last Modified:27 Jan 2022 05:34
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:0270-9139
Additional Information:This is the peer reviewed version of the following article: Martins PN, Clavien PA, Jalan R, Ghinolfi D. A Call for Randomization in Clinical Trials of Liver Machine Perfusion Preservation. Hepatology. 2020 Dec 17. doi: 10.1002/hep.31686. Epub ahead of print. PMID: 33336391, which has been published in final form at https://doi.org/10.1002/hep.31686 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. (http://www.wileyauthors.com/self-archiving)
OA Status:Green
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1002/hep.31686

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