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Treatment of phenobarbital intoxication using hemodialysis in two dogs


Basile, Jessica Kielb; Vigani, Alessio (2020). Treatment of phenobarbital intoxication using hemodialysis in two dogs. Journal of Veterinary Emergency and Critical Care, 30(2):221-225.

Abstract

Objective: To describe the use of hemodialysis in 2 dogs with severe clinical signs from phenobarbital intoxication.
Series Summary: Two dogs ingested a toxic dose of phenobarbital, leading to severe neurological dysfunction and a comatose state. Both dogs received a 3-hour session of hemodialysis with complete resolution of clinical signs and returned to normal mentation by the end of the therapy. No negative side effects occurred and phenobarbital concentrations returned to therapeutic range during treatment.
New Information Provided: This is the first report on the utility and safety of using hemodialysis for phenobarbital intoxication in dogs.

Abstract

Objective: To describe the use of hemodialysis in 2 dogs with severe clinical signs from phenobarbital intoxication.
Series Summary: Two dogs ingested a toxic dose of phenobarbital, leading to severe neurological dysfunction and a comatose state. Both dogs received a 3-hour session of hemodialysis with complete resolution of clinical signs and returned to normal mentation by the end of the therapy. No negative side effects occurred and phenobarbital concentrations returned to therapeutic range during treatment.
New Information Provided: This is the first report on the utility and safety of using hemodialysis for phenobarbital intoxication in dogs.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Department of Small Animals
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Scopus Subject Areas:Health Sciences > General Veterinary
Uncontrolled Keywords:General Veterinary
Language:English
Date:1 March 2020
Deposited On:16 Feb 2021 17:18
Last Modified:17 Feb 2021 21:01
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:1476-4431
OA Status:Closed
Publisher DOI:https://doi.org/10.1111/vec.12908

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