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Grossmann, Leoni; Yde Ohki, Cristine Marie; Döring, Christian; Hoffmann, Per; Herms, Stefan; Werling, Anna Maria; Walitza, Susanne; Grünblatt, Edna (2021). Generation of integration-free induced pluripotent stem cell lines from four pediatric ADHD patients. Stem Cell Research, 53:102268.
Human induced pluripotent stem cell (iPSC) lines have been derived from four male patients with childhood attention-deficit hyperactivity disorder (ADHD). Children and adolescents between the ages 6 and 18 suffering from ADHD were recruited for this work. Isolated keratinocytes or peripheral blood mononuclear cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and c-Myc.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > Psychiatric University Hospital Zurich > Department of Child and Adolescent Psychiatry
04 Faculty of Medicine > Neuroscience Center Zurich 04 Faculty of Medicine > Zurich Center for Integrative Human Physiology (ZIHP) |
| Dewey Decimal Classification: | 610 Medicine & health |
| Scopus Subject Areas: | Life Sciences > Developmental Biology
Life Sciences > Cell Biology |
| Language: | English |
| Date: | 24 February 2021 |
| Deposited On: | 15 Mar 2021 15:50 |
| Last Modified: | 12 Sep 2024 03:35 |
| Publisher: | Elsevier |
| ISSN: | 1873-5061 |
| OA Status: | Gold |
| Free access at: | Publisher DOI. An embargo period may apply. |
| Publisher DOI: | https://doi.org/10.1016/j.scr.2021.102268 |
| PubMed ID: | 33662736 |
Grossmann, Leoni