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Generation of integration-free induced pluripotent stem cells from healthy individuals

Yde Ohki, Cristine Marie; Grossmann, Leoni; Döring, Christian; Hoffmann, Per; Herms, Stefan; Werling, Anna Maria; Walitza, Susanne; Grünblatt, Edna (2021). Generation of integration-free induced pluripotent stem cells from healthy individuals. Stem Cell Research, 53:102269.

Abstract

Ten human induced pluripotent stem cell (iPSC) lines have been derived from five healthy controls matched to a study including Attention-Deficit Hyperactivity Disorder patients (ADHD). Both female and male children and adolescents aged 6-18 years were recruited. Isolated keratinocyte cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and cMyc.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Psychiatric University Hospital Zurich > Department of Child and Adolescent Psychiatry
04 Faculty of Medicine > Neuroscience Center Zurich
04 Faculty of Medicine > Zurich Center for Integrative Human Physiology (ZIHP)
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Life Sciences > Developmental Biology
Life Sciences > Cell Biology
Language:English
Date:24 February 2021
Deposited On:15 Mar 2021 15:51
Last Modified:12 Sep 2024 03:35
Publisher:Elsevier
ISSN:1873-5061
OA Status:Gold
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1016/j.scr.2021.102269
PubMed ID:33667761
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  • Language: English
  • Licence: Creative Commons: Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

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