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Beyond simple kinship and identification. aDNA analyses from a 17th-19th century crypt in Germany

Alterauge, Amelie; Lösch, Sandra; Sulzer, Andrea; Gysi, Mario; Haas, Cordula (2021). Beyond simple kinship and identification. aDNA analyses from a 17th-19th century crypt in Germany. Forensic Science International. Genetics, 53:102498.

Abstract

Ancient DNA (aDNA) analysis is a powerful tool in multidisciplinary research on human remains, potentially leading to kinship scenarios and historical identifications. In this study, we present a genetic investigation of three noble families from the 17th to 19th centuries AD entombed in burial crypts at the cloister church of Riesa (Germany). Tests were aimed at identifying anticipated and incidental genetic relationships in our sample and the implications thereof for the assumed identity of the deceased. A total of 17 individuals were investigated via morphological, radiographic and aDNA analysis, yielding complete and partial autosomal and Y-STR profiles and reliable mtDNA sequences. Biostatistics and lineage markers revealed the presence of first to third degree relationships within the cohort. The pedigrees of the families Hanisch/von Odeleben and von Welck were thereby successfully reproduced, while four previously unknown individuals could be linked to the von Felgenhauer family. However, limitations of biostatistical kinship analysis became evident when the kinship scenario went beyond simple relationships. A combined analysis with archaeological data and historical records resulted in (almost) unambiguous identification of 14 of the 17 individuals.

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Legal Medicine
Dewey Decimal Classification:340 Law
610 Medicine & health
510 Mathematics
Scopus Subject Areas:Health Sciences > Pathology and Forensic Medicine
Life Sciences > Genetics
Uncontrolled Keywords:Pathology and Forensic Medicine, Genetics
Language:English
Date:1 March 2021
Deposited On:23 Mar 2021 14:14
Last Modified:25 Aug 2024 01:39
Publisher:Elsevier
ISSN:1872-4973
OA Status:Hybrid
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1016/j.fsigen.2021.102498
PubMed ID:33872864
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