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Long-term outcomes of psychological treatment for posttraumatic stress disorder: a systematic review and meta-analysis

Weber, Maxi; Schumacher, Sarah; Hannig, Wiebke; Barth, Jürgen; Lotzin, Annett; Schäfer, Ingo; Ehring, Thomas; Kleim, Birgit (2021). Long-term outcomes of psychological treatment for posttraumatic stress disorder: a systematic review and meta-analysis. Psychological Medicine, 51(9):1420-1430.

Abstract

Several types of psychological treatment for posttraumatic stress disorder (PTSD) are considered well established and effective, but evidence of their long-term efficacy is limited. This systematic review and meta-analysis aimed to investigate the long-term outcomes across psychological treatments for PTSD. MEDLINE, Cochrane Library, PTSDpubs, PsycINFO, PSYNDEX, and related articles were searched for randomized controlled trials with at least 12 months of follow-up. Twenty-two studies (N = 2638) met inclusion criteria, and 43 comparisons of cognitive behavioral therapy (CBT) were available at follow-up. Active treatments for PTSD yielded large effect sizes from pretest to follow-up and a small controlled effect size compared with non-directive control groups at follow-up. Trauma-focused treatment (TFT) and non-TFT showed large improvements from pretest to follow-up, and effect sizes did not significantly differ from each other. Active treatments for comorbid depressive symptoms revealed small to medium effect sizes at follow-up, and improved PTSD and depressive symptoms remained stable from treatment end to follow-up. Military personnel, low proportion of female patients, and self-rated PTSD measures were associated with decreased effect sizes for PTSD at follow-up. The findings suggest that CBT for PTSD is efficacious in the long term. Future studies are needed to determine the lasting efficacy of other psychological treatments and to confirm benefits beyond 12-month follow-up.

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Complementary Medicine
04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Psychiatry, Psychotherapy, and Psychosomatics
Dewey Decimal Classification:610 Medicine & health
Scopus Subject Areas:Social Sciences & Humanities > Applied Psychology
Health Sciences > Psychiatry and Mental Health
Uncontrolled Keywords:Efficacy, long-term, meta-analysis, posttraumatic stress disorder, psychological treatment, PTSD
Language:English
Date:1 July 2021
Deposited On:14 Jul 2021 15:31
Last Modified:13 Mar 2025 04:35
Publisher:Cambridge University Press
ISSN:0033-2917
OA Status:Hybrid
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1017/s003329172100163x
PubMed ID:34176532
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