Hussung, Saskia; Fritsch, Ralph M (2020). Multi-target ddPCR Assays zur Detektion von KRAS- und NRAS-Mutationen. BIOspektrum, 26(6):629-634.
Detection and quantification of tumor-derived mutations in cell-free DNA (cfDNA) holds great potential for non-invasive tumor diagnosticsand molecular monitoring. We developed highly sensitive discriminatory multi-target digital droplet PCR (ddPCR) assays covering 14 KRAS and NRASS hotspot mutations.
Detection and quantification of tumor-derived mutations in cell-free DNA (cfDNA) holds great potential for non-invasive tumor diagnosticsand molecular monitoring. We developed highly sensitive discriminatory multi-target digital droplet PCR (ddPCR) assays covering 14 KRAS and NRASS hotspot mutations.
| Item Type: | Journal Article, refereed, original work |
|---|---|
| Communities & Collections: | 04 Faculty of Medicine > University Hospital Zurich > Clinic for Oncology and Hematology |
| Dewey Decimal Classification: | 610 Medicine & health |
| Scopus Subject Areas: | Life Sciences > Biotechnology
Life Sciences > Molecular Biology |
| Language: | German |
| Date: | 2020 |
| Deposited On: | 18 Aug 2021 15:59 |
| Last Modified: | 27 Jan 2022 07:32 |
| Publisher: | Spektrum Akademischer Verlag |
| ISSN: | 0947-0867 |
| OA Status: | Hybrid |
| Free access at: | Publisher DOI. An embargo period may apply. |
| Publisher DOI: | https://doi.org/10.1007/s12268-020-1463-6 |
Hussung, Saskia