Abstract
Cutaneous squamous cell carcinoma (cSCC) is the most common tumour entity that grows secondarily into the orbital area, while basal cell carcinoma (BCC) is the most common periocular and eyelid tumour. Diagnostic delays are common and may increase post-treatment complications. The therapy is challenging and must be discussed at an interdisciplinary tumour board. We discuss four cases of cSCC with orbital invasion treated with immune-checkpoint inhibitors with variable responses.
What does this study add?
- cSCC is the most common tumour entity that grows secondarily into the orbital area
- Diagnosis often may be delayed due to vague complaints
- Numbness and pain were the most common symptoms
- A rapid response rate is usually seen with anti-PD1 therapy
Nägeli, M